Citric Acid Monohydrate

Excipient (pharmacologically inactive substance)

What is Citric Acid Monohydrate?

Citric acid is a weak organic acid commonly used in the food, cosmetic and pharmaceutical industry. The parent base of citric acid, citrate, is a component of the Krebs cycle, and occurs naturally during metabolism in all living organisms. It is found naturally in citrus fruit such as lemons and limes and is used as a natural preservative. Monohydrate citric acid has one water molecule as part of it's chemical formula, and exists as a white powder.^[1][2]

Citrate or citric acid is often used to adjust pH, to add sour flavor to foods and beverages, and to form the salt derivative of minerals and metals for pharmaceuticals, as in the case of potassium citrate, a dietary supplement. According to the FDA Select Committee on Generally Recognized as Safe (GRAS) food substances, citrate salts, including citric acid, are generally regarded as safe when used in normal quantities.^[2]

Top Medications Containing Citric Acid Monohydrate

• Carbatrol 300 mg (Shire US Inc.)
• Hydroxyurea 500 mg (Teva Pharmaceuticals USA)
• Ropinirole Hydrochloride 1 mg (Glenmark Generics Inc.)
• Ropinirole Hydrochloride 0.5 mg (Glenmark Generics Inc.)
• Simvastatin 20 mg (Teva Pharmaceuticals USA)
• Simvastatin 20 mg (Aurobindo Pharma)
• Simvastatin 20 mg (Lupin Pharmaceuticals, Inc)
• Simvastatin 40 mg (Teva Pharmaceuticals USA)
• Simvastatin 40 mg (Lupin Pharmaceuticals, Inc)
• Simvastatin 40 mg (Aurobindo Pharma)
• Simvastatin 10 mg (Lupin Pharmaceuticals, Inc)
• Simvastatin 10 mg (Aurobindo Pharma)
• Simvastatin 80 mg (Lupin Pharmaceuticals, Inc)
• Simvastatin 10 mg (Teva Pharmaceuticals USA)
• Vytorin 10 mg / 40 mg (Merck & Company Inc.)
• Vytorin 10 mg / 20 mg (Merck & Company Inc.)
• Vytorin 10 mg / 80 mg (Merck & Company Inc.)
• Zelapar 1.25 mg (Valeant Pharmaceuticals Inc.)
• Zocor 20 mg (Merck & Company Inc.)
• Zocor 80 mg (Merck & Company Inc.)