Hylaform Plus

Hylaform Plus has been withdrawn from the U.S. market.

Generic Name: hylan B gel
Date of Approval: October 13, 2004
Company: Inamed Corporation and Genzyme Corporation
Treatment for: Wrinkle Correction

Hylaform Plus has been withdrawn from the U.S. market.

The U.S. Food and Drug Administration (FDA) previously approved Hylaform Plus (Hylan-B gel), a large particle size hyaluronic acid-based dermal filler that is indicated for the correction of moderate to severe facial wrinkles and folds.Hylaform Plus was developed and manufactured by Genzyme Corporation.

Hylaform Plus is a sterile, nonpyrogenic, viscoelastic, clear, colorless, transparent gel implant composed of cross-linked molecules of hyaluronan. Hyaluronan is a naturally occurring polysaccharide of the intercellular matrix in human tissues, including skin.

Hylaform Plus is injected into the dermal tissue to provide a space-occupying viscoelastic supplement for the intercellular matrix of the connective tissue. This viscosupplementation or augmentation of the dermal tissue can result in the correction of skin contour deformities caused by wrinkles or folds.

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