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  #1  
Old 06-14-2008, 11:36 AM
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Question Bacteriostatic antibiotics

Can we prescript 2 antibiotic :

Bacteriostatic & bactericidal ,


Bacteriostatic & Bacteriostatic ,

bactericidal & bactericidal



thanks
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  #2  
Old 06-15-2008, 04:29 AM
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What exactly is your question? Please use plain English in the form of a sentence.
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  #3  
Old 06-15-2008, 08:45 AM
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Exclamation the question is

Can we give to patient two antibiotics in one time depending as I written above such as :[/COLOR]
ampicillin & chloramphenicol

The first bactericidal and second bacteriostatic or

The first bactericidal and second bactericidal or

The first bacteriostatic and second bacteriostatic .


regards.
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  #4  
Old 06-15-2008, 08:48 AM
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Can we give to patient two antibiotics in one time depending on the following statments:

ampicillin & chloramphenicol


The first bactericidal and second bacteriostatic or

The first bactericidal and second bactericidal or

The first bacteriostatic and second bacteriostatic .


regards.
[/QUOTE]
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  #5  
Old 06-15-2008, 02:42 PM
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That is a question for a doctor, I don't have a license to practise medicine, however the drug interaction checker had this to say:

MONITOR: Chloramphenicol may inhibit the bactericidal effect of penicillins when used to treat bacterial meningitis and staphylococcal endocarditis. Chloramphenicol acts by inhibiting cellular protein synthesis and can change actively growing bacteria into static ones. Since penicillins work by inhibiting cell wall synthesis, their effectiveness may be reduced. In addition, neurologic toxicity may be enhanced. Data have been conflicting, and no antagonism or synergistic effects have been reported in other types of infections.

MANAGEMENT: Until more information is available, this combination should probably be reserved for conditions where it has been found to be efficacious and avoided in situations where bactericidal activity is necessary, such as certain types of bacterial meningitis or staphylococcal endocarditis. If the combination is necessary, some experts recommend administering the penicillin several hours before the chloramphenicol. Patients should be closely monitored for altered antimicrobial efficacy
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