Go Back   Drugs.com > Specialist Discussion Boards > Pharmacists
Forgotten Password?
Register FAQ Calendar Search Today's Posts Mark Forums Read

Pharmacists Drugs.com's web-based discussion board for Pharmacists, student Pharmacists, Pharmacy Technicians and student Pharmacy Technicians.

Reply
 
Thread Tools Display Modes
  #1  
Old 01-20-2009, 06:51 AM
New Member
 
Join Date: Jan 2009
Posts: 1
Default Drug interaction between Pioglitazone and Glimepiride

Dear All
I want to Know , is there any Pharmacokinetic or CYP P450 drug interaction between Pioglitazone and Glimepiride which is present in fixed dose combination product.
It will be good if any reference if available.

Thanking you in advanced
PRASHANT
Reply With Quote
  #2  
Old 02-09-2009, 11:13 PM
Member
 
Join Date: Feb 2009
Posts: 89
Default

Pioglitazone is metabolized by CYP 450 3A4 and 2C8, Glimepiride by CYP 450 2C9 so no, they are different cytochrome P450 enzymes. I do not believe there is a pharmacokinetic interaction either, but don't have REALLY solid evidence I can give you.

http://www.drugbank.ca/drugs/DB00222
http://www.drugbank.ca/drugs/DB01132
__________________
---I answer questions to the best of my ability, but with always limited knowledge of the patient's situation and obviously I can not see your chart or full medical history my advice is limited and should also be confirmed with your own doctor/pharmacist/etc. and I do not promote following my advice without proper approval from your doctor either--

Dr. B
Reply With Quote
  #3  
Old 02-10-2009, 07:34 AM
Diamond Elite
 
Join Date: Jul 2007
Location: Pacific Northwest
Posts: 8,783
Default

Quote:
Originally Posted by pmusmade View Post
Dear All
I want to Know , is there any Pharmacokinetic or CYP P450 drug interaction between Pioglitazone and Glimepiride which is present in fixed dose combination product.
It will be good if any reference if available.

Thanking you in advanced
PRASHANT




There are no known interactions between these medications I am aware of. You can check them on the "drug interactions checker" at the top of this page where indicated just below the search box. I would read up on your medications so you're more informed for your own benefit. If you do a search here on the individual medications you have the option of basic information as well as detailed information designed for professionals as well as the consumer. Enter the medications in the search box and click the drug search button.

I always suggest that members (especially those with multiple medications or medications they know little about) maintain an ongoing list of their medications in the Med Notes section of this web site. It's a great way to keep an ongoing record of our medications and all information we need to be kept informed about.

You can maintain info on several people simultaneously so it's simple to track our children's meds, our parents meds, etc. There are lots of cool benefits available on this web site for our members if you check it out. I used it for years before I ever posted on the forum. God bless.
__________________
I am not a dr. My statements are based on years of experience and related education. Consult with the professional of your choice regarding matters of concern.
Reply With Quote
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are On
Pingbacks are On
Refbacks are Off



All times are GMT -5. The time now is 06:38 AM.


Powered by vBulletin®
Copyright ©2000 - 2009, Jelsoft Enterprises Ltd.
SEO by vBSEO ©2009, Crawlability, Inc.

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18