strength of opiates compared

[detroit_boi]

some very interesting stuff...For many even eye opening...Just look at where Buprenorhine(subutex) ranks




the strength is compared to the similar dose of morphine, for example aspirin is 1/360 of morphine or 360 times less potent, etc

[Anonymous]

Db.......
glad I didn't see this when i jumped off 200mcg fent patches.....I knew i wanted to die......now i know why! Yikes!!!!!!!
I didn't have a clue what I was headed into, whoa for me ignorance was bliss,
except if i'd known this i would've gone a different route for sure....so good info!
Interesting!
Thanks
Marian

[Anonymous]

Db...
I saved this for my own info in case I ever ever ever get into a spot where a doc wants to put me on something again.
I will never again take anything without taking the responsibility onto myself to look it up and be informed.
Hopefully I will never medically be there again.
Saving just in case it gets deleted....ya never know what's fair game here!
Thanks again!

[detroit_boi]

Db...
I saved this for my own info in case I ever ever ever get into a spot where a doc wants to put me on something again.
I will never again take anything without taking the responsibility onto myself to look it up and be informed.
Hopefully I will never medically be there again.
Saving just in case it gets deleted....ya never know what's fair game here!
Thanks again!

you very welcome....This is the reason i posted this on here just to show ppl that some of the stuff they take are easier and some 100X harder to get off of. And in some cases, like yours and russ's, both fentanyl users, suboxone might have to be administered at higher doses at first to get stabilized...And for some users, suboxone should be avoided altogether, and basic tapering of might be the best and shortest rout out

[Anonymous]

Gotcha!
That's why i was so adamant and pushed Russ so hard on the subs.
That was sooooo hard for me to do!
I'm not one to push anyone on anything but wow......I knew he didn't have a clue!
Now with this info.....much easier to see it on your own!

[detroit_boi]

Gotcha!
That's why i was so adamant and pushed Russ so hard on the subs.
That was sooooo hard for me to do!
I'm not one to push anyone on anything but wow......I knew he didn't have a clue!
Now with this info.....much easier to see it on your own!

you did the right thing, even subconsciously knowing the truth. Im sure the table above will help lots of ppl in the future to decide on proper dosages, if they choose the rout

PS could you even believe there is a drug that is 100,000X stronger then morphine, even at 1/1000 of mg?!!! wow, that blew me away. It is used to dart large animals like elephants, etc, so no human for of the drug exist, but could u even imagine W/D from THAT?!!!

[dago77]

So it is saying that Sub is stronger than morphine?

[detroit_boi]

So it is saying that Sub is stronger than morphine?

YES, it says that EVEN 0.25mg of Sub is 40X stronger then 10 mg of morphine

AMAZING isnt it

PS methadone (acute) means using methadone for 1-7 days
methadone(chronic) is using methadone for extended periods of time, since it adds up in your system, just like Bupe, except it turnes out Bupe has LONGER HALF LIFE

[dago77]

I can remember the first time I got clean was at a detox center. You go there, they give it to you and then wait. This lady three 2mg pills over an hour. About 45 minutes later I couldn't see, I couldn't hold my head up. My boy had to drive the car. We went to eat after and I had to lay down in the booth!

The dr called me later to see how I was doing. I snapppped on this lady and hung up on her! Man I was so scared of those things after that. It was c/t from then on. Until years of that burned me out I figured out how to take subs. A tiny piece is all you need. That stuff is wicked dude

[detroit_boi]

bump for those who didnt see this yet

[realitycheck3r]

YES, it says that EVEN 0.25mg of Sub is 40X stronger then 10 mg of morphine
AMAZING isnt it

No, it is not amazing. This is sensationalist and it does *not* mean that Buprenorphine has 40x the anagesic and euprhoic effects of Morphine. The chart is just comparing drugs by per-milligram equivalent, which is basically binding affinity. For instance, Naloxone (Narcan) may be 30x the strength of Morphine, but obviously it has no analgesic or euphoric effects.

Buprenorphine is a partial agonist, which is why it's used for opiod dependence. It's high binding affinity is why the chart lists it as '40x Morphine', but that is just the strength in which it binds to the receptors. It's *effects* are completely different than a full agonist like Morphine. It has little to no euphoric effects, limited analgesic effects, and a ceiling after which no additional dose increases the effects (once all opiod receptors are occupied). That's why patients in treatment never increase their dose. It's one of the few drugs where patients can be stabilized for years on the same dose. This is not the case of full agonists, where the more you take, the higher you get.

Even better, since Buprenorphine so strongly binds to the receptors, it has a blockade effect, meaning that a person could not get high on a full agonist like Morphine, Oxycodone, etc.. for up to *days* after a single dose of Buprenorphine.

So, take this as a milligram equivelence chart, and remember that each opiod has different effects, though most of the full agonists are similar, but the partial agonists (Buprenorphine) and antagonists (Naloxone) are not even in the same class as far as narcotic effects.

Dispelling the sensationalism, felt it my duty....