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Aspirin overdose
  1. #1
    withwhomilivalie is offline Junior Member
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    Default Aspirin overdose

    Hey does anyone know how many 325mg aspirin pills you would have to take to OD? I've been trying to find out how many mg you would have to take or SOMETHING but all I can find is like 10mg/kg and I don't know how to put that in a form that says about X number of pills will cause a serious overdose.
    I'm doing a paper for school on NSAIDS and that information would be very much appreciated from anyone who can help! Thanks a bunch.

    -Katie

  2. #2
    iggynthestooges is offline Junior Member
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    Hey Katie,
    I dont know the answer to your quesiton but I would love to know it myself! Someone asked me that question just 2 days before this post was up. I'll get back to you if I find anything. ^-^
    -Iggy

  3. #3
    sweetchikk05 is offline Banned
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    Boy, what is it with you and asprin first your friend took 12 and was sick, then it was 16, now your writing a paper?? try to google and see what you come up with, oh wait I am sorry you dont like me I almost forgot does that mean I am not allowed to give you advice??

    Liz Ann

  4. #4
    withwhomilivalie is offline Junior Member
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    no I am greatful for any advice you would give me, liz ann..it was tylenol my friend took, not aspirin. I'm writing a paper on NSAIDS in general for my class. The only thing I've found on google was 150mg/kg of body weight and I don't know how in the world ot translate that into a rough # of pills. Someone told me they thought a lethal dose was around 30 pills. Does that sound right?

  5. #5
    sweetchikk05 is offline Banned
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    This is the information I looked up and found for you, it says more than 20gms it potentionally fatal...I also did a little reasearch to try and convert it for you to see how many tablets that would be and I couldnt figure it out in tablets, I bet if you were to call a local pharmacy and ask them how many tablets of tylenol makes up 20 grams they may be able to help you but I will still give you the calculations that I came up with..
    20 grams= 20000milligrams
    20grams=0.70600 ounces
    20 grams=0.02000killigrams
    I wish I could figure out how many tablets that would be but I never was too good with that sort of math, I hope the information I found is useful to you.

    Acetaminophen Maximun Dosage

    Question: What is the toxic dosage of the acetaminophen? How many tablets are safe to take? What is the Lethal dosage? Also, If your tolerance increases, and you feel no effect from your current dose, Is it safe to increase or is the lethal dose the same regardless of your tolerance?

    Answer: The daily limit of acetaminophen varies by weight and size. Some patients will experinece liver toxicity at lower doses than others. 10-15 gms can be hepatoxic and greater than 20 gm are potentially fatal. We usually don't recommend more than 3 gm a day. Higher sustained doses would require occasional liver function tests. Your tolerance to acetaminophen does not change. Your tolerance and ability to handle narcotics does. If you need more pain relief, increase the narcotics, not the acetaminophen.


  6. #6
    heva_eyre is offline New Member
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    Default lethal dose of asprin is variale

    150mg/kg means a 70kg man would need around 35 tablets
    and a 60 kg woman (9st ish) would need 30, for a child under 8st it would be less than 25 tablets

    Heather

  7. #7
    streetdoc1 is offline New Member
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    Default re: asprin overdose

    If someone has not already answered your question regarding how many 325mg asprin it would take to OD this may help. A lethal dose of ASA is considered to be an amount that exceeds 500mg/kg. This calculates to approximately 1539 325mg tabs or 6173 81 mg tabs. This would be a lethal dose for a 100kg/220 lb. person.I hope this helps.
    Last edited by streetdoc1; 04-06-2009 at 08:27 AM. Reason: incomplete data

  8. #8
    Kiyoraka is offline New Member
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    A lethal dose of Aspirin is 500 mg/kg of body weight.

    Since 1 kg = 2.2 lb, divide body weight (in pounds) by 2.2 to find body weight in kilograms:

    100 lbs / 2.2 = 45.45 kg
    120 lbs / 2.2 = 54.55 kg
    150 lbs / 2.2 = 68.18 kg
    220 lbs / 2.2 = 100.0 kg

    Then, multiply body weight (in kg) by 500 to calculate the lethal dose:

    45.45 kg x 500 = 22,725 mg
    54.55 kg x 500 = 27,275 mg
    68.18 kg x 500 = 34,080 mg
    100.0 kg x 500 = 50,000 mg

    This lethal dose, divided by 325 mg, yields the number of 325 mg tablets in a lethal dose:

    22,725 mg / 325 mg = 70 tablets
    27,275 mg / 325 mg = 84 tablets
    34,080 mg / 325 mg = 105 tablets
    50,000 mg / 325 mg = 154 tablets

  9. #9
    pain8852 is offline New Member
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    Well, the doses previously mentioned are to tell how many would likely bring death from an overdose. However, it is not reccommended that anyone for any reason take more than 4 grams of aspirin(roughly 12 tablets if 325 mg). If anyone does ingest more than 6.5 grams of aspirin(20 or more tablets if 325 mg), it is suggested that this person seeks medical care. On a side note, however, I survived from 30 to 35 aspirin without any medical help. I do not suggest this in any way however. It will mess you up for days.

  10. #10
    hamsterbytes54 is offline New Member
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    Default best answer

    Quote Originally Posted by pain8852 View Post
    Well, the doses previously mentioned are to tell how many would likely bring death from an overdose. However, it is not reccommended that anyone for any reason take more than 4 grams of aspirin(roughly 12 tablets if 325 mg). If anyone does ingest more than 6.5 grams of aspirin(20 or more tablets if 325 mg), it is suggested that this person seeks medical care. On a side note, however, I survived from 30 to 35 aspirin without any medical help. I do not suggest this in any way however. It will mess you up for days.
    http://www.drugs.com/enc/aspirin-overdose.html Go here for the known best answer. no guessing. says 20 pills at 325 mg is what will take to severely overdose. so 30 is what I took, since I only had that many. threw in 10 Tylenol just to make sure.

  11. #11
    lamartin37 is offline New Member
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    Hi Katie, I don't know if you have received a satisfactory answer yet but here is my story. When I was 16 I tried to commit suicide by ingesting 40 aspirin. I layed in bed that night waiting for death to overtake me. What I experienced was ringing in my ears all night long and dosing on and off. The next morning, feeling disappointed I was not dead, and disoriented, I went to school. Shortly after arriving at school I started throwing up white foam. I went to the nurses office and my dad was called to pick me up. About every 15 minutes on the way home I threw up on the side of the road. I didn't die as was planned, and I also don't know what long term effects it had on my body. I think about that sometimes and am thankful and glad I didn't die as I am 58 years old today and have had a wonderful life, one I wouldn't have otherwise had. I can't stress how important it is to seek a good friend, a pastor, or professional help if the feelings of suicide or depression overtake you. When we are young, and in that state of mind, we only see our life in front of us imagining nothing will change. We think we will feel helpless and hopeless forever and we are so wrong. We aren't born in this life to become disposable, but with a purpose. I am thankful to have God, and my faith to help me see that.

  12. #12
    greenfingers15 is offline New Member
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    Quote Originally Posted by lamartin37 View Post
    Hi Katie, I don't know if you have received a satisfactory answer yet but here is my story. When I was 16 I tried to commit suicide by ingesting 40 aspirin. I layed in bed that night waiting for death to overtake me. What I experienced was ringing in my ears all night long and dosing on and off. The next morning, feeling disappointed I was not dead, and disoriented, I went to school. Shortly after arriving at school I started throwing up white foam. I went to the nurses office and my dad was called to pick me up. About every 15 minutes on the way home I threw up on the side of the road. I didn't die as was planned, and I also don't know what long term effects it had on my body. I think about that sometimes and am thankful and glad I didn't die as I am 58 years old today and have had a wonderful life, one I wouldn't have otherwise had. I can't stress how important it is to seek a good friend, a pastor, or professional help if the feelings of suicide or depression overtake you. When we are young, and in that state of mind, we only see our life in front of us imagining nothing will change. We think we will feel helpless and hopeless forever and we are so wrong. We aren't born in this life to become disposable, but with a purpose. I am thankful to have God, and my faith to help me see that.
    would you mind ever so much describing the aftermath - long term?

    it is rather important for me.

  13. #13
    MarziDayziCrazi is offline New Member
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    [QUOTE=lamartin3
    I can't stress how important it is to seek a good friend, a pastor, or professional help if the feelings of suicide or depression overtake you. When we are young, and in that state of mind, we only see our life in front of us imagining nothing will change. We think we will feel helpless and hopeless forever and we are so wrong. We aren't born in this life to become disposable, but with a purpose. I am thankful to have God, and my faith to help me see that [/QUOTE]
    Thank you for sharing your painful and ultimately positive experience with us, I'm relieved and happy for you in that you were unsuccessful in your attempt, yet, very successful in continuing to live a good life, that like you so bravely pointed out, would not have happened had it of been the outcome you thought you wanted
    I, too, at 16, wanted "out" and while I had no plan or method I felt I couldn't do it anymore, being abused in every way possible, on the night I thought it was going to happen, God blessed me with an Angel, his name is Randall, that saved me, made me care and feel sorrow and sadness for someone other than myself, in time, I realized how unfairly selfish it would have been and when I'm in a serious doldrums state it is My Beloved Randall who still, 31plus years after, that gently, yet firmly, keeps me from making a decision that while I think it will solve my problem, it will bring devastation to those who love me, including my precious meowmeows (cats) and he does so with the help of My Beloved Angels Davi and Skahti and so MANY more! All beloved, all beautiful and I'm SO Thankful! We ALL have Angels, we just need to talk to them, listen, feel, be open, but I'll save that for another forum, I'm sharing as I did to say how God has saved and blessed me via My Angels and I'm 47 going on 48 soon and so very Thankful, yes, again and ALWAYS, that I'm here! I'm alive! The nights are long, pretty and my solace, my place in the Moon, I'd love it, by the way, I'd there are any Nyctophiliac Pluviophiles out there that would like to chat...
    My biggest worry, is that the NSAID essay is a cover to find out the actual amount needed to achieve a fatal overdose, I'm sincerely sorry if I'm out of line or completely wrong, but after what I and so many others have been through, I tend to see requests like that in a jaded way, however, I truly apologize if your information seeking is altruistic, I want that to be the honest truth however redundant that appears because I'm a survivor that still has moments thinking I'd be better off "out" and it's just not so! Help is out there, people WILL listen and guide you, talk to you, take my and others' stories and glean from them, if the answers provided, and soundly presented are they, kudos to you all!, are helpful to your paper and you're really writing about NSAID's and their effects, you've hit the jackpot, I'm praying that is so and for continued success in your studies and in living life and each and everyone who replied, read or will read and reply, life TRULY is worth living even when those sketchy moments invade, have Faith, Trust God and Praise Jesus...Amen
    Be well and blessed all,
    MarZiDayZi

  14. #14
    Iluv2smile is offline Platinum Member
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    Katie
    It is more like 300-500 mg per kg
    Say you have a 72 kg pt or 162 lbs
    You take will use 400 mg/ kg
    400 X 72= 28,800 mg
    There are 325 mg in one Reg Asa
    28,800mg divided by 325mg = 88.61 pills
    Hope this helps..

    There are ranges for salicylate toxicity... usually between 150 mg/ kg - 500 mg/ kg

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