[sylviagreier]

does anyone know how long a typical dose lasts in the system & when can I expect pain relief to be at a maximum?

[Excursor4690]

Concerning Tylenol: A typical dose lasts about 4-6 hours with an onset of relief within the first half hour. Maximum pain relief occurs within an hour and a half. However, tylenol is a weak pain killer and these figures work for mild pain such as a headache, and other mild pains/cramps. Tylenol by itself generally will not help with moderate/severe pain. Hope this helps.
Cheers,
L.C