I had came down with a head ache so i decided to take a couple asprin. and when i went to wash them down with a glass of coke my grandmother allmost had a heart attack saying that i should never do that. Now i was aware about alcohol and pain killers don't mix. But soft drinks? I don't exactly take my grandmothers word on any of this. Considering i drink coke most of the time and i'v washed down all my pills with this. and it didn't seam to effect me. but she claimed that drinking it with coke made you high. anyways i feel like a complete idiot even asking this question. but it dosent hurt to ask other peoples opinion on this. I have herd that often times a soft drink will cancel the effect of the pill that dosent sound illogical. or possibly the excessive caffine in the drink might alter the effect of the pill. But nothing really significant. anyways, anybody got any comments on this feel free to respond.