I am new to this site but need some advise. I have been taking carisoprodol for 3 days 2-3 times a day (as directed), also taking celebrex 1 x day and hydrocone apap 7.5 every 4-6 hrs as needed. Then on top of that I take zoloft and trimethoprim. Yesterday my feet started swelling up and today I think it is the carisoprodol because I have taken the other med's with no problem. Is this an allergic reaction? I am going to not take any the rest of today and tomorrow and see if the swelling goes down and if it continues then I will call my doctor and tell him what is going on.