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Can drinking on Antabuse heighten your blood alcohol when submitting to a field sobriety test? How does antabuse cause the metabolism of alcohol to change? Thanks...
Antabuse (disulfiram) works by inhibiting the enzyme acetaldehyde dehydrogenase.
When ingested, alcohol is converted to acetaldehyde rapidly. It is acetaldehyde which causes nausea, vomiting, flushing and palpitation.
Normally acetaldehyde is further converted to other metabolites by acetaldehyde dehydrogenase, but when this enzyme is inhibited, acetaldehyde accumulates in blood to cause the above symptoms to deter further drinking.
Antabuse and Blood Alcohol Level 
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