[skyline21]

Hi, im new to this forum and i just want to ask something...Dyphenhydramine(sp?)...This is the active ingredient in benadryl as a anti-histamine. I was wondering if you could overdose on benadryl? I have followed the directions to take 2 at a time, but i do not find it effective to suppress the symptoms of pink eye. My eyes were itching like hell one time, so i took about 8 in a 12 hour period. I took 2 pills before bed, and then in the morning i took about 6 more. Maybe like after about 2 hours of consumption, i felt all weird. I felt like i was all slow motion, like i felt kinda floaty. You know the feeling when your in a swimming pool and your just like standing there moving your limbs, and its all slow and all. Thats how it felt. Especially my head. I was scared i might of taken too much all at one time. I thought i was going to pass out. Can overdosing on dyphenhydramine be fatal? Thats my question.

[Stallion]

there have been reports of people taking up to 700mg of benadryl and surviving, but this is an extreemly large dose, and it could certainlly be fatel to a person w/ lower tolorance to the drug. benedryl has an LD50 of 500mg per kilo in rats, but this number is probably much lower pwer kilo in humans. So yes, you can die by eating too much benadryl, it is a potent anticholinogenic and in large doses (250-600mg) can produce a hallucinatory delerium similar to jimson weed intoxication that can last for a day or two. more info on benadryl at
http://www.erowid.org/pharms/diphenh...ydramine.shtml

Information = Freedom

[Tovey]

A baby died from benedryl overdose, when the babysitter put benedryl into the formula, because the baby was being fussy, and the sitter thought that would make the baby sleepy. It was in the newspaper, maybe a year ago. Sadly, it shows a drug that can be helpful if taken correctly, but taken in overdose, can kill.

[paulis7217]

Yes, the effects of a benedryl over dose are very serious. I am a kid who used to abuse a lot of different drugs until this past weekend. I had taken benadryl before to trip off of it, but last weekend i decided to step it up and take 36 of them. I was starting to feel the effects and i realized something wasnt normal. I went to the emergency room and it only got worse. My heart rate jumped up to 175 beats per minute and i nearly had a heart attack. I had to have my stomach pumped and was in ICU for 2 days. Thats my experience with benadryl and it changed my life.

[bshaun2]

Originally Posted by Stallion

there have been reports of people taking up to 700mg of benadryl and surviving, but this is an extreemly large dose, and it could certainlly be fatel to a person w/ lower tolorance to the drug. benedryl has an LD50 of 500mg per kilo in rats, but this number is probably much lower pwer kilo in humans. So yes, you can die by eating too much benadryl, it is a potent anticholinogenic and in large doses (250-600mg) can produce a hallucinatory delerium similar to jimson weed intoxication that can last for a day or two. more info on benadryl at
http://www.erowid.org/pharms/diphenh...ydramine.shtml

Information = Freedom

I take alot of this stuff, yes i do abuse it. However the only reason i take so many benadryl is because i can get a great buzz, it's super cheap, and it's 100% non habit forming. I take anywhere from 500-800mg 2 or three times a day and have been doing so for quite awhile. And other than some dry mouth,and a bit of short term and memory loss theres no problem. These issues go away quite quickly.