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Old 08-21-2005, 07:43 PM
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Default Codeine

Hi guys,
I have been taking quite alot of codeine lately due to sinus headaches. I am also taking exfexor for depression. I have been extremely depressed lately and wondered if the codeine could be reacting with the anti depressant. Has anyone ever experienced this or maybe have some information for me? I would be very grateful.
Lisa
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Old 08-22-2005, 07:31 AM
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What other drugs will affect codeine?
• Do not take codeine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. Dangerous side effects could result.
• The most serious interactions affecting codeine are with those drugs that also cause sedation. The following drugs may lead to dangerous sedation if taken with codeine:
· antihistamines such as brompheniramine (Dimetane, Bromfed, others), diphenhydramine (Benadryl, Nytol, Compoz, others), chlorpheniramine (Chlor-Trimeton, Teldrin, others), and others;
· tricyclic antidepressants, such as amitriptyline (Elavil) and doxepin (Sinequan), and serotonin reuptake inhibitors such as fluoxetine (Prozac), sertraline (Zoloft), and paroxetine (Paxil);
· other commonly used antidepressants, including amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), and protriptyline (Vivactil);
· anticholinergics such as belladonna (Donnatal), clidinium (Quarzan), dicyclomine (Bentyl, Antispas), hyoscyamine (Levsin, Anaspaz), ipratropium (Atrovent), propantheline (Pro-Banthine), and scopolamine (Transderm-Scop);
· phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Prolixin), thioridazine (Mellaril), and prochlorperazine (Compazine); and
· tranquilizers and sedatives such as phenobarbital (Solfoton, Luminal), amobarbital (Amytal), secobarbital (Seconal), alprazolam (Xanax), diazepam (Valium), lorazepam (Ativan), flurazepam (Prosom), and temazepam (Restoril).
• Do not take any of the drugs listed above without the approval of your doctor.
• Drugs other than those listed here may also interact with codeine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.


Effexor is a SSNRI, Seratonin and Norepinephrine Reuptake Inhibitor, so it can cause problems if taken with codeine!

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My information is not guaranteed correct. I do not get them right all the time, but I do enjoy the hunt~
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Old 08-22-2005, 05:54 PM
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Thankyou very much for your answer. I had already read and researched this information. Unfortunately it doesn't state if mixing these drugs causes an increase of depression.
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