[Rubi]

Is anyone out there taking Seasonale suffering from irritability or depression? If so, how long have you been taking it and how long have you been experiencing these problems?

[Jacqui Rives]

I am just starting my fourth week of Seasonale and definitely feel like I am much more irritable and feel depressed. Started Seasonale to aleviate migraine attacks that come with my period nearly every month. Despite the irritability and depression, I am virtually headache free so far although it may be too soon to tell. Did not expect theses as side effects.