a metabolite of a drug is what you body converts the drug into after it enters you system. a metabolite is considered active if it has a theraputic effect equal to or greater than the effect of the accual drug. For example:
Carisoprodol (soma) metabolizes ito meprobomate in the body, which is a moderatly powerful sedative. This active metabolite is considered to be the primary cause of
Soma's sedating properties. An analogue is a drug which is chemiclly very similar to another drug, but has small molecular differences (like molocules bonded at the same site but pointing in different directions in 3D space. Analogues may have a similar effect to the analogous drug. If you need anymore info, let me know what your specific case is and I may be of more assistance. Hope this helps
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