There is a PDR Drug information for Nitrostat tablets on Drugs.com. It is at
http://www.drugs.com/pdr/nitrostat_tablets.html
It includes a table with pharmacokinetic information (table 1). There are two things I don't understand:
First, the AUC is expressed in mins. Is that correct?
Secondly, the t1/2 is shorter than tmax. It is my understanding that when you administer the drug sublingually the concentration in blood will increase, reaching a Cmax after Tmax mins, then it decreases. At t1/2, the concentration should be half of the initial concentration. So, t1/2 should be always longer than tmax. Is that correct? If not, please explain the data in the table.
Can someone help me out with these questions? (I have a project to submit by the end of this week and the only pharmacokinetic data I have found are these)
Thank you very much in advance.
Eugen