Flagyl (metronidazole) when taken with
lithium may increase the risk of lithium toxicity.
Lithium levels should be monitored more closely whenever
metronidazole is added to or withdrawn from therapy, and the lithium dosage adjusted as necessary.
You should notify your doctor if you experience early symptoms of lithium toxicity such as diarrhea, vomiting, drowsiness, tremor, lack of coordination, ataxia, or muscular weakness.