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Old 11-10-2004, 09:55 PM
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Join Date: Nov 2004
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Default Info/opinons on Mirtazapine? Seroquel?

Hi,

I'm severely clinically depressed (and have anxiety problems too). The latest medications I've been on are Mirtazapine for the depression and a low dose of Seroquel for the other issues.

I've been on both drugs for almost three months now. The Seroquel isn't having any discernible effect at all, and the Mirtazapine seemed like it was starting to kick in after about two weeks but then STOPPED again--I had one week of feeling a little better and then I slid back to square one.

So I told all this to my psychiatrist and said I'd like to switch to something else. (It wouldn't be the first time something has inexplicably stopped working for me--it happened before with Prozac, as my psychiatrist knows.) He refused to prescribe me something different, saying that these kinds of drugs can take a while to kick in. He told me to keep taking the same meds/same dosage for another two months(!) and check in with him then.

I know antidepressants can take awhile to work, but I've only ever heard 6-8 weeks--NOT five months! Plus everything I've read about antidepressants says that their effects are typically gradual and cumulative--this peak-and-drop I experienced doesn't fit.

Interestingly, I just tried to Google some info to back me up (which is how I found this site). The entry for Mirtazapine on here says something about its long-term effectiveness not being known because they've never done any drug trials that lasted longer than SIX WEEKS. I get a very strong feeling that this psychiatrist isn't giving my problems proper consideration. Can anyone else confirm this?
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