[Skip]

I have had the Vicodin ES 7.5/750 APAP that tread M357.
I recently went to a different pharmacy and the vicodin generic they gave me said Watson 387 on it.

Both of these pills are 7.5/750 APAP generics for Hydrocodone.
So my big concern is why is it that when I take the Watson stuff, I'm don't feel it the same as the M367 and the pain relief is different???
Is one better than the other or??
Thanks
SK

[Denny]

You are not alone in your suspicion. The Watson brand of pain killers do NOT work as well as others. Endo is a safe choice and Mallincort (spelled wrong I'm sure but close) is sort of in third place. If you search the forum you will find others in agreement with me on this. You are the consumer...don't be shy about asking for a particular brand name when you get your 'scripts filled. A pharmacist who does not like you asking about brands is not worth working with anyway. Good luck..D.

[X-JUNKIE]

Sorry,but the answer you received---IS WRONG!!!!!!
I'll log on tomorrow with the right answer.Sorry,I have to make you wait--I have a baby to put to sleep. I'm also sorry,you were given false info.

[Denny]

Hi Skip - Your other responder should look up the word "OPINION". Most people could easily see by how my note was worded that it is an opinion and not a text book answer! As far as I know the whole idea of an opinion is that there is no "wrong" answer. I gave you the best info. I could based on my own use and from the feedback I get from my customers during the forty hours a week I work dispensing medication at a large pharmacy. Just trying to help! Again, good luck and if nothing else you can take this to the bank... the Watson products suck!

[painkiller]

I have extensive experience with different variations of Hydrocodone. Mallinckrodt or the M3XX pills seem to be the most effective for me. Watson's usually do not work as well for me, with the expection of Watson 540. Those are the most effective that I've ever had. They are 10/500 and light blue. I'd recommend trying those.
-painkiller

[Skip]

Well, Im convinced the watsons are terrible.. At least for my body chemistry.
I have taken up to 5 and hardly feel any pain releif or euphoric feeling where i can take 1-2 mallinkrodt hydro ES 7.5/750 and have the pain gone etc..
Pretty dissappointing thta these dont work and Ive paid for them.

I alos just got this Hydrocodone after a root canal called
Lorcet 10mg/650..
I have no idea what they are and havent tried them yet.
they are light blue with that says 3597 on one side and a cursive looking V on the opposite.
I cantr seem to find it on the pill Identifier.
I mean I know what it is but Id like to know more about it.

Thanks for the input everyone.

Ya know, I would rather not take anything and have no pain that to be on pain meds...

[tracilynn]

As someone who has had all three different pills, the name brand, and both generic, I will tell you that I have experienced nothing different between the three.

I hope this helps you!
Traci

[Frtwynr2]

Well it doesn't matter if it's watson or regular vicodin. It's the same ingredients = same effect. DUH

[benjetking]

As far as generic Hyrdrocodone goes....what you feel in the difference depends on the amount of caffeine (a-pap) in the actual batch..otherwise they are all the same! Stops the pain and lets you feel good.

[Cats Meow]

APAP is acetaminophen, not caffeine, and all generics are not equal, but hydrocodone is usually very consistant.

[spikey59]

Morons,
Everyone here should do some research before randomly answering questions thinking they are right. Your ignorance is your own fault. All drug information is available on the web and drug manufacture websites. Watson, Endo, Mallinkrodt whoever have to follow the same FDA guidelines for drug approval in the US. Meaning, in order to be legally substituted as a generic for a brand name they have to show IDENTICAL blood levels, duration, etc. as the brand. Which means all "AB" rated generics will work EXACTLY the same with EXACTLY the same active ingredients. Also, there is a drug identifier ON THIS WEBSITE for use by the general public. I would recommend in the future, if you have any questions about medications ask your pharmacist or doctor, not random people on the web. They could give you wrong advice and information. Be aware of what you put into your body, it's YOUR responsibility.

As a side note, if you have problems with one generic vs. another, it's probably in your head. The brain is easily fooled.

-CPhT

[Javababe1970]

Originally Posted by spikey59

Morons,
Everyone here should do some research before randomly answering questions thinking they are right. Your ignorance is your own fault. All drug information is available on the web and drug manufacture websites. Watson, Endo, Mallinkrodt whoever have to follow the same FDA guidelines for drug approval in the US. Meaning, in order to be legally substituted as a generic for a brand name they have to show IDENTICAL blood levels, duration, etc. as the brand. Which means all "AB" rated generics will work EXACTLY the same with EXACTLY the same active ingredients. Also, there is a drug identifier ON THIS WEBSITE for use by the general public. I would recommend in the future, if you have any questions about medications ask your pharmacist or doctor, not random people on the web. They could give you wrong advice and information. Be aware of what you put into your body, it's YOUR responsibility.

As a side note, if you have problems with one generic vs. another, it's probably in your head. The brain is easily fooled.

-CPhT

Spikey,

I am not sure if you are aware of this or not, but this is a discussion forum. A discussion forum is where people discuss topics of interest, often sharing their experiences.

You shared your opinion and par-took in this discussion, yet called everyone else a moron and ignorant in reference to their part in this discussion.

People in discussion forums often discuss things. FYI, here is the definition for discuss: : "to investigate by reasoning or argument b: to present in detail for examination or consideration <discussed plans for the party> c: to talk about".

Next time you enter into a discussion forum, why don't you try presenting your information without knocking everyone else around you? I am sure you have a lot to offer, but I think everyone can do without the name calling and superiority complex.

[abalone]

I have cronic knee pain and my doctor prescribed generic Norco 10/325.I prefer Watson Norco 10/325 (yellow),They seem to work and take away my pain alot better than the generic! Sincerely abalone

[abalone]

[QUOTE=abalone;225618]I have cronic knee pain and my doctor prescribed generic Norco 10/325.I prefer Watson Norco 10/325 (yellow),They seem to work and take away my pain alot better than the generic.The only thing is I have kaiser with a $10 co-pay,I have to pay $30 for the Watson brand

[Blazed24sevn]

Originally Posted by abalone

I have cronic knee pain and my doctor prescribed generic Norco 10/325.I prefer Watson Norco 10/325 (yellow),They seem to work and take away my pain alot better than the generic! Sincerely abalone

Spikey is actually correct... i am a pharmacist and FDA guidelines DO NOT allow Pharm. companies to put in any extra ingredients into there medications... so ALL the generics are the same... which means they cannot work differently and its all in your head.. Its not matter of opinion.. its matter of FACT!!! You can say this forum is about opinion, but most of your opinions are wrong and your feeding people a bunch of wrong information.. ALL GENERICS ARE THE SAME, JUST LOOK DIFFERENT. ANY DIFFERENCES YOU FEEL ARE IN YOUR HEAD... OR MAYBE BECAUSE YOUR TAKING A DIFFERENT MG!!

[Blazed24sevn]

Originally Posted by Skip

I have had the Vicodin ES 7.5/750 APAP that tread M357.
I recently went to a different pharmacy and the vicodin generic they gave me said Watson 387 on it.

Both of these pills are 7.5/750 APAP generics for Hydrocodone.
So my big concern is why is it that when I take the Watson stuff, I'm don't feel it the same as the M367 and the pain relief is different???
Is one better than the other or??
Thanks
SK

The reason so are feeling different is this reason.... You named 3 different medications calling them all 7.5/750 hydrocodone apap... well heres the problem. The first one you named is the M357... which is 5/500 Hydrocodone APAP, a smaller MG than the 7.5 ES. The second one you named was the Watson 387 which is the 7.5/750 APAP! Then you name the M367 WHICH IS A 10/325 APAP, a HIGHER MG than the 7.5. THIS IS WHY YOU "THINK" THE GENERICS ARE WORKING BETTER, cause what you were taking was a 10mg vicodin and not a 7.5 and the M357 is a 5mg vicodin!! Your are taking all different mg's of the drug!

[Blazed24sevn]

Originally Posted by Denny

You are not alone in your suspicion. The Watson brand of pain killers do NOT work as well as others. Endo is a safe choice and Mallincort (spelled wrong I'm sure but close) is sort of in third place. If you search the forum you will find others in agreement with me on this. You are the consumer...don't be shy about asking for a particular brand name when you get your 'scripts filled. A pharmacist who does not like you asking about brands is not worth working with anyway. Good luck..D.

The watson are the SAME as all others.... Each Pharm. Company makes different Hydrocodone mgs for different pills as well as different asprin levels too... but if its got the same asprin and hydrocodone in it IT WILL WORK EXACTLY THE SAME... This lady was taking a 5/500mg APAP, a 7.5/750mg APAP, and a 10/325mg APAP Hydrocodone and thinking they were all 7.5/750... THIS IS WHY THEY ALL WORK DIFFERENTLY... the watson is the 7.5.... M367 is a 10/325 and a M357 is a 5/500 apap... you learn something before you try and teach people something that is NOT EVEN TRUE!

[xenon10]

The FDA rigorously defends generics as being "bio-equivalent" to the "innovator" drug. Is it? It seems it starts out that way. The FDA claims that the average variability is 4%, yet it does not require a new bio availability study to be submitted unless it is shown to be +/- 25%. From the federal regulation (42 FR 1648) SubPart B pa.320.21 "Requirement for submission for in vivo bioavailability and bioequivelence data" states (e)(2) (g) Any person holding an approved full or abbreviated new drug application shall submit to FDA a supplemental application containing new evidence demonstrating the in vivo bioavailability or bioequivalence of the drug product that is the subject of the application if notified by FDA that:"
(1) "There are data demonstrating significant intrabatch variability, e.g.,plus or minus 25% of the bioavailability of the drug product. "

***So, what we have here is a bit of a shell game. Whereas the initial application is stringent, once approved, the manufacturer need only resubmit testing if the FDA "catches" it producing a drug with greater than +/- 25%. So they are correct when they say it is very close (initially), what happens after that seems very lenient. At least, that's how I read it. I have read of a study that exposed some drugs to as much as a 31% variation. I'm sorry I couldn't locate that study again.

[washpatech]

Okay let me try to set some stuff straight here. Alot of people are right in here. First off. The meds she is taking are different strengths. Second of all, all generics that ARE the same strength ALL have the same medicine in them. Therefore they should ALL work the same..BUT....here is the kicker. Even though different companies make generics with the same strength does NOT mean the are made exactly the same. I was a nurse for years and I was very interested in learning that the slight variations in the meds, will cause a quicker onset, absorbtion time, and lenght they will last. A persons body chemistry will ALSO contribute in this factor. Everyones body chemistry is different and even the slightest variation of a med will affect a persons body differently. So there are many truths to what everyone is saying but some people are way off in saying that it will all work the same.

[PassingBy]

The law (FDA) states that generic versions of brand name narcotic pain killers contain 85%....

(sources and drugs vary, but I'm of the understanding that the allowed variation is as low as 70% for some drugs and as high as 95% for others...)

....or more of the active ingredient. It allows for variation, which is in turn taken full advantage of by the drug manufacturers.

This isn't made up, it's a fact.

If you think that your generic brand of Vicodin isn't working as well as the brand name works, chances are you are probably right.

I would think that any Pharmacist worth their salt would know that.

[PassingBy]

Originally Posted by Blazed24sevn

Spikey is actually correct... i am a pharmacist and FDA guidelines DO NOT allow Pharm. companies to put in any extra ingredients into there medications... so ALL the generics are the same... which means they cannot work differently and its all in your head.. Its not matter of opinion.. its matter of FACT!!! You can say this forum is about opinion, but most of your opinions are wrong and your feeding people a bunch of wrong information.. ALL GENERICS ARE THE SAME, JUST LOOK DIFFERENT. ANY DIFFERENCES YOU FEEL ARE IN YOUR HEAD... OR MAYBE BECAUSE YOUR TAKING A DIFFERENT MG!!

You're not a Pharmacist.

You are full of ********, though.

[merciles]

You're the one full of sh*t for posting bad info deliberatley..


From the fda website:

Generic Drug
A generic drug is the same as a brand name drug in dosage, safety, strength, how it is taken, quality, performance, and intended use. Before approving a generic drug product, FDA requires many rigorous tests and procedures to assure that the generic drug can be substituted for the brand name drug. The FDA bases evaluations of substitutability, or "therapeutic equivalence," of generic drugs on scientific evaluations. By law, a generic drug product must contain the identical amounts of the same active ingredient(s) as the brand name product. Drug products evaluated as "therapeutically equivalent" can be expected to have equal effect and no difference when substituted for the brand name product.


http://www.fda.gov/Drugs/Information...cm079436.htm#G

Have a nice day