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Hydrocodone/Oxycodone
  1. #1
    anonone17 is offline Junior Member
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    Default Hydrocodone/Oxycodone

    Hi i was wondering if someone could tell me the Similarities and Differences between Hydrocodone and Oxycodone. I thought that the two were very similar but am not sure. Any help at all on this topic will be greatly appriciated. Thanks!

  2. #2
    anonone17 is offline Junior Member
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    Also if anyone knows could you tell me the simlarities and differences between those two and codeine as well. Thanks!

  3. #3
    anonone17 is offline Junior Member
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    and one more thing.... Does anyone know if any drug companys plan to comeout with a extended relese version of the drug hydrocodone and why hasn't one been put out already. Anyone know? thanks

  4. #4
    zippysgoddess is offline Platinum Member
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    Well hydrocodone is a strong pain med, but Oxy is much, much stronger. Oxy is even stronger than Morphine on a two to three basis, so if you were taking say Oxy 20mgs Controlled Release, a generic version of Oxycontin, and you have to switch to Morphine, you have to take 30mgs of the Controlled Release morphine to hit and equivelent dosage. Hydrocodone has the same conversion rate, so the Oxy is much stronger.

    As to the time released issues, well I am not sure, it is possible that it is harder to control the release of Hydro, so that may be why it is not available in a controlled release form yet.



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  5. #5
    Cats Meow is offline Banned
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    My feeling is, if the drug company's made hydrocodone any stronger the FDA would classify it as schedule 2 where as hydro is schedule 3 and doesn't have as strict prescribing and dispensing regs. I believe this is why we will never see hydro in a pure form, better we damage our livers with acetaminophen.

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  6. #6
    zippysgoddess is offline Platinum Member
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    Cats, it is available now with Ibuprofen, instead of just Acetaminophen. In the past few months they released several including Vicoprofen.



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  7. #7
    Cats Meow is offline Banned
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    Yes, I knew that Zippys', I think it would be good to see the drug companies come out with an even lower dose then 325mg of acetaminophen, say make it 100mg.
    I would be interested to know if you think my hypothesis regarding scheduling are plausible?

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  8. #8
    zippysgoddess is offline Platinum Member
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    Well, that really isn't just a hypothesis, it is a fact, the only reason Acetaminophen is in those, is to keep it a lower scheduled drug, there is really no point for the Acetaminophen to be in the drug, it does not augment the efficacy of the drugs it is coupled with or anything.

    It has already been tried by various companies, to release a med of just Hydro, the FDA would not approve it, they said it is far to dangerous and addictive, so the only way these companies can keep it on the market is to couple it in a low dose with the other med. Anytime the FDA has had to review it for approval on a higher schedule that have denied it, and refused to let it be put on the market that way.



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  9. #9
    mrbrew is offline Member
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    Hey all,

    The newpill out now for hydrocodone is called Hycodan. It is almost pure hydro. It is 5 mg of hydrocodone and 1.5 mg. Homatropine Methylbromide, USP. It also comes in syrup. Doctors are only writing scripts for this due to unproductive coughing. Meaning if you have a terrible cough and you are not producing anything from it, (a dry cough) then a doctor might write you a script for the tablets or syrup. Theose are the only two active ingredients in this med. Everyting else is just filler.

    mrbrew

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  10. #10
    chipmunk is offline New Member
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    Red face hydrocodonevsoxycodone

    I have taken both percocet 5/325 and vicodin 5/500 with my flexeril 10 mg I know percocet works better than vicodin. I would love to quit taking narcotics but he pain is too severe I dislocated my shoulder last sunday in May I can not afford the therapy but I live with discomfort daily I only take my narcotic at night becasue of the drowiness.

  11. #11
    Businessman1 is offline Member
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    I'm not sure that hydrocodone is any more dangerous or addictive than oxycodone, or any of the other strong opiate pain meds.

    Codeine is one of the three natural opiates (the others being morphine and thebaine).

    Hydrocodone and Oxycodone are synthetic opiates known as opioids - chemically altered for increased potency.

    Codeine is the weakest of the 3 you asked about and is considered to have a lower potential for abuse. It produces less euphoria and less pain relief. In many countries it is available over the counter when mixed with ibuprofen or acetaminophen.

    Hydrocodone is 15 times stronger than codeine. In the US it is schedule 2 when in preparations of more than 15MG as well as when it is on its own (without acetaminophen or ibuprofen) due to a seperate law. it is 66% of the strength of oxycodone. Mixing it DOES increase it's pain relieving properties as well as reducing it's potential for abuse.

    Oxycodone is available on it's own and is schedule 2 even when mixed. It is the strongest of the three and produces the most euphoria. Some people (myself included) find it much less sedating than hydrocodone. The different strengths refer only to pain relieving properties (not euphoria).

    My view is that there is no point in pure or slow release formulation of hydrocodone because for pain that is severe enough to require it, doctors would probably prescribe stronger meds like Oxycodone, morphine and hydromorphone. It also lasts a little longer than all of the above to start with.

  12. #12
    xTerm is offline Junior Member
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    Even though oxy works better for pain relief than hydro, I prefer hydro over oxy hands down as oxy makes me sooo sleepy and gives me a "drugged" out feeling.
    Hydro just makes me kind of hyper, not bouncing off the walls hyper but whatever im doing when i take hydro i really get into it, its weird.
    The only drawback is the acetaminophen in it and im taking the Norco, which contains the lowest amount of aceta you can get without getting a compound (325mg), plus i take more than im supposed to, i get 180 a month and run out early every month.
    I bought some Milk Thistle though and am hoping that it will give my poor liver some much needed help.

    Oh and Damn its my lucky day, ive been out for one week and I find 3 norco in a pair of pants this morning
    Last edited by xTerm; 09-04-2009 at 10:27 AM.

  13. #13
    alex107 is offline New Member
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    Default the Differences between Oxycodone/Hydrocodone..

    Basically the differences between the two is that Hydrocodone is a little bit stronger than Tylenol because its mixed with about 10% of Oxycodone. (Pain reliever) and 90% Tylenol. NOW oxycodone is all pain relief 100%. It's whats in the Vicoden (hydrocodone) that makes you feel good or have no pain. Its just the pure form of the pain reliever. That's the easiest way to explain it....So again HYDROCODONE is mixed with a small amount of Oxycodone and a lot of Tylenol.. OXYCODONE is the Pure NO mixing of Tylenol. Hope this helps you out, best advice try and stay with the Hydrocodone its alot less addicting than the Oxycodone.

  14. #14
    xTerm is offline Junior Member
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    Not to be rude alex.. but are you high? that made no sense at all.. hydrocodone is its own drug and a little bit weaker than oxycodone.
    hydrocodone by itself is a schedule II drug, just like oxycodone but ive never heard of anyone getting pure hydro.
    Hydro mixed with other drugs, like tylenol is what almost everyone gets, norco, vicodin, lortab etc.
    Oxycodone, like oxycontin is pure narcotic, nothing added and like i said, its stronger than hydro.
    Your last point is right though, if you can get by with hydro then dont move up to oxy, both are very addictive though and the withdrawals are hell.

  15. #15
    845mx5 is offline New Member
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    hey everyone. Im new to the board but have been on oxycontin for 2 or 3 years. I dont understamd why anyone thinks the fda wont make pure hydrocodone pills because of abuse or it being highly addictive. That makes no sense. oxycodone is way more addictive and stronger then hydrocodone, so if they have oxycontin, pure oxycodone plus fillers, they have fentanyl patches which is insanely strong to an person who has not taken opiates so whats the real reason they wont make pure HYDROcodone pills? One other thing. (i could be wrong but from what i understand) all opiates are converted into morphine in your liver. so does that mean the morphine is what releives pain and causes euphoria or is it converted after the effects have taken place?

  16. #16
    Titty Puff is offline Junior Member
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    Quote Originally Posted by 845mx5 View Post
    hey everyone. Im new to the board but have been on oxycontin for 2 or 3 years. I dont understamd why anyone thinks the fda wont make pure hydrocodone pills because of abuse or it being highly addictive. That makes no sense. oxycodone is way more addictive and stronger then hydrocodone, so if they have oxycontin, pure oxycodone plus fillers, they have fentanyl patches which is insanely strong to an person who has not taken opiates so whats the real reason they wont make pure HYDROcodone pills? One other thing. (i could be wrong but from what i understand) all opiates are converted into morphine in your liver. so does that mean the morphine is what releives pain and causes euphoria or is it converted after the effects have taken place?
    No, only Codeine metabolizes into Morphine in some people's livers (everyone's different). It does break down into Morphine but sometimes will not show on a drug test as previously just stated. Also, Morphine will also show up on a drug test. Hydromorphone and Oxymorphone may also show up as Morphine but this is unknown still. They can test for Hydromorphone separately and I don't believe any drug tests can detect Oxymorphone as of yet.

    Oxycodone & Hydrocodone are all derived from the poppy plant, in which so is opium; specifically Hydrocone and Oxycodone are derived from thebaine chemical of the poppy plant. Morphine is a chemical of the poppy plant as well and codeine is also derived from Morphine and even dormant and dominant in some species of the plant.
    Last edited by ddcmod; 07-13-2011 at 12:31 AM.

  17. #17
    Titty Puff is offline Junior Member
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    Oh also I believe Fentanyl may also show up as Morphine but I don't know. I do know Fentanyl is 10,000 times more potent than morphine, which is why even the highest Fentanyl patch is 100mcg per hour, equivalent to 10mg of morphine per hour. Fentenayl is adminstered in MICROGRAMS, while other narcotic opiate pain killers are administered in MILIGRAMS. So imagine how much more potent Fentanyl is. I was shot up with it when I broke my back and also was on the pain patches, the strongest 100mcg/hour ones.

    1 microgram = 0.001 milligrams

  18. #18
    Popperincess12 is offline New Member
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    OXYCODONE does mix with tylonol...its called "percocet"

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