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Old 03-20-2009, 10:20 PM
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Default Gemfibrozil Tab 600mg

Does anyone know why this drug is to be taken 30 min before meals? Is there a reaction or is it harmful if taken either with the meal or after the meal. We forget it so many times until he is in middle of his meal. Thanks for any information you know.
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Old 03-22-2009, 11:58 AM
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Here, this is taken from the product monograph.

Gemfibrozil pharmacokinetics are affected by the timing of meals relative to time of dosing. In one study (ref. 4), both the rate and extent of absorption of the drug were significantly increased when administered 0.5 hour before meals. Average AUC was reduced by 14-44% when LOPID was administered after meals compared to 0.5 hour before meals. In a subsequent study (ref. 4), rate of absorption of LOPID was maximum when administered 0.5 hour before meals with the Cmax 50-60% greater than when given either with meals or fasting.

In other words, it works way more effectively. Harmful, no.

Gemfibrozil (Lopid), harmful yes, don't take this drug if you're pregnant or nursing (but I guess you're a Granny).

Last edited by Cats Meow; 03-22-2009 at 12:03 PM.
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