[carly]

Can anyone tell me what are some of the side effects of taking Wellbutrin and Prozac together? I have a friend whom the doctor has put her on both of these drugs. She has been taking them for a little over a month now. She just had her first seizure yesterday, which has had no history of having seizures in the past. If anyone can help it would be greatly appreciated.......
Thanks,
Carly

[Twizted]

[V] Dear Carly, Wow, your friend had no prior problems with seisures?
And now has had a seissure??? "********"...
Thanx for the info, better look into this more indepth. Twizted

Hi, I need to know what about Wellbutrin???

[Stallion]

Sounds like this docor has his head up his ass. Mixing antidepressants is a really bad idea, esp if they both work to regulate seritonin, as prozac and wellbutrin both do. Seizures are a very common symptom of seritonin syndrome, which results for too much seritonin left floating in the synaptic gaps of the brain. It can be life threatening, and she should certainly not continue taking both. I don't know which one would be better to discontinue. you should talk to a (different) doctor about what to do for recovering from this gross neglegence on the part of her doc, and perhaps also a lawyer.

Information = Freedom

[sfc420]

It doesnt take an expert like Stallion to point that one out - That would cause the whackiest side effects you'll ever imagine.

[flipflopbug]

I have been taking wellbutrin and prozac together for over 9 months and I'm just fine. I take 300mg of Wellbutrin and 80mg of Prozac. Sometimes it IS necessary to be on higher doses of these meds. The max. dose of Prozac is 80mg and the max. dose of Wellbutrin is 450mg. They both work differently and make a good team. It's been working for me for almost a year. I also take Risperdal and Clozaril.

[Nonyuh]

Originally Posted by Stallion

Sounds like this docor has his head up his ass. Mixing antidepressants is a really bad idea, esp if they both work to regulate seritonin, as prozac and wellbutrin both do. Seizures are a very common symptom of seritonin syndrome, which results for too much seritonin left floating in the synaptic gaps of the brain.

Information = Freedom

Wellbutrin is a aminoketone, it has little to no effect on serotonin. Any serotonergic effect would be from its suppression of enzymes that regulate metabolism in the liver, much in the same way that grapefruit interacts with many drugs. Doctors quite often prescribe "cocktails" of antidepressants, sometimes it's the only way to get results with treatment resistant patients.

Wellbutrin/buproprion has been known to trigger seizures on its own, though it's not common. Without more information, it's hard to say whether it was the subject's sensitivity to the buproprion, too high a dosage of buproprion, an interaction with something else, what dosage of Prozac her Dr. had her on, etc.