I have been on pain meds for over ten years. Five back surgeries done within a year, Hardware put in, taken out , replaced, What a freakin pain , However, I have imflamation, Pain in my legs mainly lower legs never never ends. Pain meds help my back and thighs, but not the lower legs. I have been on it all too. I took myself off the long acting meds and now just do the Lortab. I started taking 800mg of Curcumin three times a day. OMG, Praise the Lord, The pain in my lower legs is almost completely gone. I am LOVING this. Now I am down to two pain pills a day, I feel so freaking good. I wish everyone could try this, It takes about three days before you can tell, but keep up with it. Some days I take four pills. Please try this, it works. Plus the anticancer benefits are amazing.