Floxin (ofloxacin) Alcohol, Food & Lifestyle Interactions

There is 1 food and lifestyle interaction with Floxin (ofloxacin):

ADJUST DOSING INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics. Absorption may also be reduced by sucralfate, which contains aluminum, as well as other polyvalent cations such as iron and zinc. The mechanism is chelation of quinolones by polyvalent cations, forming a complex that is poorly absorbed from the gastrointestinal tract. The bioavailability of ciprofloxacin has been reported to decrease by as much as 90% when administered with antacids containing aluminum or magnesium hydroxide.

MANAGEMENT: When coadministration cannot be avoided, quinolone antibiotics should be dosed either 2 to 4 hours before or 4 to 6 hours after polyvalent cation-containing products to minimize the potential for interaction.

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Floxin (ofloxacin) drug Interactions

There are 465 drug interactions with Floxin (ofloxacin)

Floxin (ofloxacin) disease Interactions

There are 7 disease interactions with Floxin (ofloxacin) which include:

Colitis Cns Disorders Qt Interval Prolongation Crystalluria

Diabetes Hemodialysis Renal Dysfunction

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