Depo-Provera (medroxyprogesterone) and Alcohol / Food Interactions
There are 3 alcohol/food/lifestyle interactions with Depo-Provera (medroxyprogesterone) which include:
High Blood Pressure (Hypertension)
Moderate Potential Hazard, Moderate plausibility
estrogens/progestogens - fluid retention
Estrogens and progestogens may cause fluid retention, particularly when given in high dosages or for prolonged periods. Therapy with these agents should be administered cautiously in patients who have preexisting problems with excess fluid. In addition, patients with conditions that may be adversely affected by fluid accumulation, such as asthma, epilepsy, migraine, and cardiovascular or renal dysfunction, should be observed for exacerbation of their condition during estrogen and/or progestogen therapy. High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)
Moderate Potential Hazard, Moderate plausibility
progestogens - hyperlipidemia
Some progestogenic agents may elevate plasma LDL levels and/or lower HDL levels, although data have been inconsistent. Patients with preexisting hyperlipidemia may require closer monitoring during progestogen therapy, and adjustments made accordingly in their lipid-lowering regimen. Obesity
Minor Potential Hazard, Moderate plausibility
progestogens - weight gain
Progestogens can cause weight gain, which may be significant (as is the case with parenteral medroxyprogesterone) and undesirable in obese patients attempting to lose weight.You should also know about...
Depo-Provera (medroxyprogesterone) drug Interactions
There are 169 drug interactions with Depo-Provera (medroxyprogesterone)
Depo-Provera (medroxyprogesterone) disease Interactions
There are 10 disease interactions with Depo-Provera (medroxyprogesterone) which include:
Breast Malignancy- Liver Disease
- Thromboembolism
Depression- Fluid Retention
- Glucose Intolerance
- Thyroid Function Tests
- Bone Mineral Density
- Hyperlipidemia
- Weight Gain
See also...
- Side Effects of Depo-Provera (medroxyprogesterone)
- Depo-Provera (medroxyprogesterone) Consumer Information
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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