Lo / Ovral (ethinyl estradiol / norgestrel) and Alcohol / Food Interactions
There are 7 alcohol/food/lifestyle interactions with Lo / Ovral (ethinyl estradiol / norgestrel) which include:
ethinyl estradiol ↔ Alcohol (Ethanol)
Minor Drug Interaction
Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
For a clinical details see professional interaction data.
norgestrel ↔ Alcohol (Ethanol)
Minor Drug Interaction
Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
For a clinical details see professional interaction data.
ethinyl estradiol ↔ food
Minor Food Interaction
Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
For a clinical details see professional interaction data.
High Blood Pressure (Hypertension)
Severe Potential Hazard, High plausibility
estrogens - hypertension
The risk of myocardial infarction and strokes, including those associated with oral contraceptive use and some estrogen use, is increased in patients with hypertension. Moreover, estrogens (and also progestogens) may elevate blood pressure and worsen the hypertension, thus compounding the risk. Clinically significant blood pressure increases have been reported during estrogen therapy, particularly in patients receiving high dosages or treated with oral contraceptive combinations having high progestational activity. These effects also increase with duration of therapy and patient age. Therapy with estrogens should be administered cautiously in patients with preexisting hypertension. Patients should be monitored for changes in cardiovascular status, and their antihypertensive regimen adjusted or estrogen therapy withdrawn as necessary. In patients requiring contraception, alternative methods should be considered for those who are hypertensive, over age 35, and smoke.High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)
Moderate Potential Hazard, Moderate plausibility
estrogens - hyperlipidemia
Although estrogens have generally favorable effects on plasma lipids, including increases in HDL and decreases in total cholesterol and LDL, they have also been associated with significant elevations in triglyceride levels, particularly when high dosages are used. Severe hyperlipidemia is known to sometimes cause pancreatitis. Patients with preexisting hyperlipidemia may require closer monitoring during estrogen therapy, and adjustments made accordingly in their lipid-lowering regimen.High Blood Pressure (Hypertension)
Moderate Potential Hazard, Moderate plausibility
estrogens/progestogens - fluid retention
Estrogens and progestogens may cause fluid retention, particularly when given in high dosages or for prolonged periods. Therapy with these agents should be administered cautiously in patients who have preexisting problems with excess fluid. In addition, patients with conditions that may be adversely affected by fluid accumulation, such as asthma, epilepsy, migraine, and cardiovascular or renal dysfunction, should be observed for exacerbation of their condition during estrogen and/or progestogen therapy.High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)
Moderate Potential Hazard, Moderate plausibility
progestogens - hyperlipidemia
Some progestogenic agents may elevate plasma LDL levels and/or lower HDL levels, although data have been inconsistent. Patients with preexisting hyperlipidemia may require closer monitoring during progestogen therapy, and adjustments made accordingly in their lipid-lowering regimen.Obesity
Minor Potential Hazard, Moderate plausibility
progestogens - weight gain
Progestogens can cause weight gain, which may be significant (as is the case with parenteral medroxyprogesterone) and undesirable in obese patients attempting to lose weight.You should also know about...
Lo / Ovral (ethinyl estradiol / norgestrel) drug Interactions
There are 479 drug interactions with Lo / Ovral (ethinyl estradiol / norgestrel)
Lo / Ovral (ethinyl estradiol / norgestrel) disease Interactions
There are 19 disease interactions with Lo / Ovral (ethinyl estradiol / norgestrel) which include:
Abnormal Vaginal Bleeding
Carcinomas (Estrogenic)
Hypercalcemia In Breast Cancer
Hypertension
Thromboembolism/Cardiovascular
Hepatic Neoplasms
Breast Malignancy
Liver Disease
Thromboembolism
Gallbladder Disease
Hypercalcemia
Hyperlipidemia
Liver Disease
Depression
Fluid Retention
Glucose Intolerance
Thyroid Function Tests
Hyperlipidemia
Weight Gain
See also...
- Side Effects of Lo / Ovral (ethinyl estradiol / norgestrel)
- Lo / Ovral (ethinyl estradiol / norgestrel) Consumer Information
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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