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Sirturo and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with Sirturo (bedaquiline).

Moderate

bedaquiline food

Moderate Food Interaction

Food significantly increases the absorption of bedaquiline. Therefore, you should take each dose of bedaquiline with food. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication in treating tuberculosis. Avoid alcohol during treatment with bedaquiline, as it may increase the risk of liver damage. You should seek immediate medical attention if you develop signs and symptoms of liver damage such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Sirturo drug interactions

There are 558 drug interactions with Sirturo (bedaquiline).

Sirturo disease interactions

There are 5 disease interactions with Sirturo (bedaquiline) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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