Norco (acetaminophen / hydrocodone) and Alcohol / Food Interactions
There is 1 alcohol/food/lifestyle interaction with Norco (acetaminophen / hydrocodone):
acetaminophen ↔ Alcohol (Ethanol)
Major Drug Interaction
Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Switch to professional interaction data
HYDROcodone ↔ Alcohol (Ethanol)
Moderate Drug Interaction
Consumer information for this interaction is not currently available.
GENERALLY AVOID: The central nervous system-depressant effects of opioid analgesics and ethanol may be additive. The combination of these agents may result in additive CNS-depression and impairment of judgment, thinking, and psychomotor skills. In more severe cases, respiratory depression, hypotension, profound sedation, and coma can occur. Death has been reported in overdosage.
MANAGEMENT: The concomitant use of opioid analgesics and ethanol should be avoided.
You should also know about...
Norco (acetaminophen / hydrocodone) drug Interactions
There are 618 drug interactions with Norco (acetaminophen / hydrocodone)
Norco (acetaminophen / hydrocodone) disease Interactions
There are 19 disease interactions with Norco (acetaminophen / hydrocodone) which include:
Alcoholism- Liver Disease
- Impaired Gi Motility
- Infectious Diarrhea
- Liver Disease
- Prematurity
- Renal Dysfunction
- Acute Alcohol Intoxication
- Drug Dependence
- Hypotension
- Intracranial Pressure
- Respiratory Depression
Pku- Adrenal Insufficiency
- Biliary Spasm
- Hypothyroidism
- Seizure Disorders
- Urinary Retention
- Arrhythmias
See also...
- Side Effects of Norco (acetaminophen / hydrocodone)
- Norco (acetaminophen / hydrocodone) Consumer Information
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. Multum's drug information does not endorse drugs, diagnose patients, or recommend therapy. Multum's drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2013 Multum Information Services, Inc. The information in contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
