Post-splenectomy syndrome can occur after surgery to remove the spleen. It consists of a group of symptoms and signs such as:
- Destruction of red blood cells
- Increased risk of getting severe infections, from bacteria such as Streptococcus pneumoniae and Neisseria meningitidis
- Thrombocytosis (increased platelet count, which can cause blood clots)
Possible long-term medical problems include:
- Hardening of the arteries (atherosclerosis)
- Pulmonary hypertension (a disease affecting the blood vessels in your lungs)
Connell NT, Shurin SB, Schiffman FJ. The spleen and its disorders. In: Hoffman R, Benz EJ Jr, Silberstein LE, Heslop HE, Weitz JI, eds. Hematology: Basic Principles and Practice. 6th ed. Philadelphia, Pa: Saunders Elsevier; 2012:chap 162.
|Review Date: 3/3/2013
Reviewed By: Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, Bethanne Black, Stephanie Slon, and Nissi Wang.