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Culture - duodenal tissue biopsy

Definition

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A duodenal tissue culture is a laboratory exam to check a piece of tissue from the first part of the small intestine (duodenum) for infection-causing organisms.

Alternative Names

Duodenal tissue culture

Why the Test is Performed

A culture of duodenal tissue is done to check for bacteria that may lead to certain illnesses and conditions. For example, it can check for Helicobacter pylori, which may cause peptic ulcer disease.

How the Test is Performed

A piece of tissue from the first part of the small intestine is taken during an upper endoscopy (esophagogastroduodenoscopy).

The sample is then sent to a lab, and placed in a special dish (culture media) that allows bacteria or viruses to grow. The sample is placed under a microscope and checked at regular time periods to see if there are any organisms present and if they are growing.

Any organisms that grow on the culture are identified.

How to Prepare for the Test

This article discusses the culture test. For information on how to prepare for an upper endoscopy and biopsy procedure, see esophagogastroduodenoscopy.

Normal Results

No harmful bacteria are found.

What Abnormal Results Mean

An abnormal finding means that harmful bacteria has been found in the tissue sample. This may include Helicobacter pylori (especially if ulcers are present) and organisms that cause inflammation of the stomach and intestines, such as:

  • Salmonella
  • Campylobacter
  • Giardia
  • Entamoeba
Review Date: 9/25/2006
Reviewed By: Charlotte Grayson, MD, Private Practice specializing in Internal Medicine and Infectious Disease, Smyrna, GA. Review provided by VeriMed Healthcare Network.
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