Buccal smear

Alternative Names: Sex chromatin test

A buccal smear (pronounced "buckle") is the painless removal of a sample of cells from the lining of the mouth (inside of the cheek) for study.

Why is the Test Performed?

The procedure is used to obtain cells for chromosome and DNA analysis,most often for genetic testing. The International Olympic Committee adopted the test many years ago to help detect male imposters among female athletes. When the test is used in this way, it's called the sex chromatin test. This method may also help establish the sexual identity of newborns.

How is the Test Performed?

The health care provider will gently scrape the inside of the cheek with a small spatula to collect cells for testing.

Preparation for the Test

Rinse and wash the mouth as instructed.

How will the Test Feel?

You will feel a scraping sensation as cells are removed from the cheek.

Buccal smear Risks

There are no risks.

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Learn more about Buccal smear

Review Date: 12/15/2010
Reviewed By: Frank A. Greco, M.D., Ph.D., Director, Biophysical Laboratory, The Lahey Clinic, Burlington, MA. Review provided by VeriMed Healthcare Network. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
Do not use this information for medical emergencies - Call 911. This information should not be used for the diagnosis or treatment of any medical condition. A licensed medical practitioner should always be consulted for diagnosis and treatment of any and all medical conditions. Links to other websites do not constitute endorsements and are provided for information only. Any duplication or distribution of this information is strictly prohibited.
Copyright 2012 A.D.A.M., Inc.
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