Bone marrow aspiration

Alternative Names: Iliac crest tap; Sternal tap

Bone marrow is the soft tissue inside bones that helps form blood cells. It is found in the hollow part of most bones. Bone marrow aspiration is the removal of a small amount of this tissue in liquid form for examination.

See also:

• Bone marrow biopsy
• Bone marrow culture

Why is the Test Performed?

Your doctor may order this test if you have abnormal types or numbers of red or white blood cells or platelets on a complete blood count. This test is used to diagnose:

• Anemia (some types)
• Infections
• Leukemia
• Other blood disorders

It may help determine whether cancers have spread or responded to treatment.

How is the Test Performed?

Bone marrow aspiration may be done in the health care provider's office or in a hospital. The bone marrow will be removed from your pelvic or breast bone. Occasionally, another bone is selected.

The health care provider will clean the skin and apply a numbing medicine (local anesthesia) to the area and surface of the bone. Next, a special needle is inserted into the bone. The needle has a tube attached to it, which creates suction. A small sample of bone marrow fluid flows into the tube. The needle is removed.

A laboratory specialist looks at the bone marrow fluid under a microscope.

Preparation for the Test

Tell the health care provider:

• If you are allergic to any medications
• If you are pregnant
• If you have bleeding problems
• What medications you are taking

You must sign a consent form for the procedure.

How will the Test Feel?

You will feel a sting and slight burning sensation when the numbing medicine is applied. You may feel pressure as the needle is inserted into the bone, and a sharp and sometimes painful sucking sensation as the marrow is removed. This feeling lasts for only a few moments.

On rare occasions, patients are given medicine to help them relax.

Bone marrow aspiration Risks

There may be some bleeding at the puncture site. More serious risks, such as serious bleeding or infection, are very rare.

Considerations

This test is often performed when there are problems with various types of blood cells. The person may be at increased risk for bleeding, infection, or other problems.

Normal Results for Bone marrow aspiration

The bone marrow should contain the proper number and types of:

• Blood-forming (hematopoietic) cells
• Connective tissues
• Fat cells

What Abnormal Results Mean

Abnormal results may be due to:

• Acute lymphocytic leukemia (ALL)
• Acute myelogenous leukemia (AML)
• Chronic lymphocytic leukemia (CLL)
• Chronic myelogenous leukemia (CML)
• Disseminated bacterial or fungal infections
• Idiopathic thrombocytopenic purpura (ITP)
• Lymphoma
• Multiple myeloma
• Myelofibrosis
• Myelodysplastic syndrome (MDS)
• Primary thrombocytopenia
• Waldenstrom's macroglobulinemia

Bone marrow aspiration	Sternum - view of the outside (anterior)

Review Date: 6/2/2010
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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