Blind loop syndrome

Blind loop syndrome occurs when part of the intestine becomes bypassed. Digested food slows or stops moving through part of the intestines. This causes bacteria to grow too much in the intestines and leads to problems in absorbing nutrients.

Causes of Blind loop syndrome

The name of this condition refers to the "blind loop" formed by the bypassed intestine. This blind loop does not allow digested food to flow normally through the intestinal tract.

When a section of the intestine is affected by blind loop syndrome, the bile salts needed to digest fats become ineffective. This leads to fatty stools and poor absorption of fat and fat-soluble vitamins. Vitamin B12 deficiency may occur because the extra bacteria that develop in this situation use up all of the vitamin.

Blind loop syndrome is a complication that occurs:

• After many operations, including subtotal gastrectomy (surgical removal of part of the stomach) and operations for extreme obesity
• As a complication of inflammatory bowel disease

Diseases such as diabetes or scleroderma may slow down movement in a segment of the intestine, leading to blind loop syndrome.

Blind loop syndrome Symptoms

• Diarrhea
• Fatty stools
• Fullness after a meal
• Loss of appetite
• Nausea
• Unintentional weight loss

Tests and Exams

During a physical examination, the doctor may notice a mass in, or swelling of, the abdomen. Possible tests include:

• Abdominal CT scan
• Abdominal x-ray
• Blood tests to check nutritional status
• Upper GI series with small bowel follow through contrast x-ray

Treatment of Blind loop syndrome

Treatment generally starts with antibiotics for the excess bacteria growth, along with vitamin B12 supplements. If antibiotics don't work, surgery to help the food flow through the intestine may be considered.

Prognosis (Outlook)

Many patients get better with antibiotics. If surgical repair is needed, the outcome is usually very good.

Potential Complications

• Complete intestinal obstruction
• Death of intestine (intestinal infarction)
• Hole (perforation) in intestine
• Malabsorption and malnutrition

When to Contact a Health Professional

Call your health care provider if you have symptoms of blind loop syndrome.

References

Semrad CE. Approach to the patient with diarrhea and malabsorption. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 142.

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