Bernstein test
Alternative Names: Acid perfusion test
The Bernstein test is a method to reproduce symptoms of heartburn. It is usually done with other tests to measure esophageal function.
Why is the Test Performed?
The test attempts to reproduce symptoms of gastroesophageal reflux (stomach acids coming back up into the esophagus).
How is the Test Performed?
The test is done in a gastroenterology laboratory. A nasogastric (NG) tube will be inserted through one side of your nose and down into your esophagus. Mild hydrochloric acid will be sent down the tube, followed by salt water (saline) solution. This process may be repeated several times.
You will be asked to tell the health care team about any pain or discomfort you have during the test.
Preparation for the Test
You should not eat or drink anything for 8 hours before the test.
How will the Test Feel?
You may have a gagging feeling and some discomfort when the tube is put into place. The acid may cause symptoms of heartburn. Your throat may be sore after the test.
Bernstein test Risks
There is a risk of gagging or vomiting.
Normal Results for Bernstein test
The test results will be negative.
What Abnormal Results Mean
A positive test suggests that the symptoms are caused by esophageal reflux of acid from the stomach.
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Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
Copyright 2011 A.D.A.M., Inc.



