Edarbyclor

Generic Name: azilsartan and chlorthalidone (AY zil SAR tan and klor THAL i done)
Brand Names: Edarbyclor

What is Edarbyclor?

Edarbyclor contains a combination of azilsartan and chlorthalidone. Azilsartan is an angiotensin II receptor antagonist. Azilsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. Chlorthalidone is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Edarbyclor is used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Edarbyclor is sometimes given together with other blood pressure medications.

Edarbyclor may also be used for purposes not listed in this medication guide.

Important information about Edarbyclor

Do not use Edarbyclor if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant. You should not use Edarbyclor if you are allergic to azilsartan (Edarbi) or chlorthalidone (Thalitone), or if you are unable to urinate.

Before you take Edarbyclor, tell your doctor if you have kidney or liver disease, an electrolyte imbalance (low levels of potassium or magnesium in your blood), congestive heart failure, or if you are dehydrated.

Drinking alcohol can further lower your blood pressure and may increase certain side effects of Edarbyclor. Do not use potassium supplements or salt substitutes while you are taking Edarbyclor, unless your doctor has told you to.

Your blood pressure will need to be checked often. Visit your doctor regularly.

Keep using Edarbyclor as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Before taking Edarbyclor

You should not use Edarbyclor if you are allergic to azilsartan (Edarbi) or chlorthalidone (Thalitone), or if you are unable to urinate.

To make sure you can safely take Edarbyclor, tell your doctor if you have any of these other conditions:

• kidney disease;

• gout;

• an electrolyte imbalance (such as low levels of potassium in your blood);

• a history of heart disease or stroke; or

• if you are dehydrated.

FDA pregnancy category D. Do not use Edarbyclor if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant. Edarbyclor can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control while taking this medicine. It is not known whether azilsartan and chlorthalidone passes into breast milk or if it could harm a nursing baby. You should not breast-feed while taking this medicine. Do not give Edarbyclor to anyone under 18 years old without medical advice.

How should I take Edarbyclor?

Take Edarbyclor exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Edarbyclor may be taken with or without food.

Your blood pressure will need to be checked often. Visit your doctor regularly.

Conditions that may cause very low blood pressure include: vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low salt diet, or taking diuretics (water pills). Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

Keep using Edarbyclor as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Edarbyclor is only part of a complete program of treatment that may also include diet, exercise, weight control, smoking cessation, and other medications. Follow your doctor's instructions very closely. Changing any of these factors can affect your blood pressure.

To be sure Edarbyclor is not causing harmful effects, your kidney function may need to be tested. Visit your doctor regularly.

Store Edarbyclor in the original container at room temperature, away from moisture, heat, and light.

See also: Edarbyclor dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.

What should I avoid while taking Edarbyclor?

Drinking alcohol can further lower your blood pressure and may increase certain side effects of Edarbyclor. Do not use potassium supplements or salt substitutes while you are taking Edarbyclor, unless your doctor has told you to. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

See also: Edarbyclor and alcohol (in more detail)

Edarbyclor side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Edarbyclor: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• feeling like you might pass out;

• urinating less than usual or not at all;

• drowsiness, confusion, mood changes, increased thirst, loss of appetite, vomiting;

• swelling, weight gain, feeling short of breath; or

• electrolyte imbalance (dry mouth, extreme thirst, drowsiness, restless feeling, confusion, nausea and vomiting, increased or decreased urination, constipation, muscle pain or weakness, fast heart rate, or seizure (convulsions)).

Less serious Edarbyclor side effects may include:

• diarrhea, nausea, upset stomach;

• mild skin rash;

• cough;

• mild dizziness; or

• weakness, tired feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Edarbyclor side effects (in more detail)

What other drugs will affect Edarbyclor?

Tell your doctor about all other medicines you use, especially:

• other blood pressure medications;

• digoxin (Lanoxin, Lanoxicaps);

• lithium (Lithobid);

• any other diuretic (water pill); or

• a non-steroidal anti-inflammatory drug (NSAID) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others.

This list is not complete and other drugs may interact with Edarbyclor. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about Edarbyclor.