Zaltrap (ziv-aflibercept) Drug Interactions
30 major drug interactions
65 moderate drug interactions
Medications known to interact with Zaltrap (ziv-aflibercept)
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ACAM2000 (smallpox vaccine)
ActHIB (haemophilus b conjugate (prp-t) vaccine)
ActHIB with DPT (diphtheria toxoid / haemophilus b conjugate (prp-t) vaccine / pertussis, acellular / tetanus toxoid)
Adacel (Tdap) (diphtheria toxoid / pertussis, acellular / tetanus toxoid)
adalimumab
Afluria (influenza virus vaccine, inactivated)
Afluria 2012-2013 (influenza virus vaccine, inactivated)
Afluria Preservative-Free 2012-2013 (influenza virus vaccine, inactivated)
Agriflu (influenza virus vaccine, inactivated)
alefacept
alemtuzumab
Amevive (alefacept)
anakinra
anthrax vaccine adsorbed
Aplisol (tuberculin purified protein derivative)
Aplitest (tuberculin purified protein derivative)
Arava (leflunomide)
Arcalyst (rilonacept)
Attenuvax (measles virus vaccine)
Aubagio (teriflunomide)
Azasan (azathioprine)
azathioprine
bcg
Biavax II (mumps virus vaccine / rubella virus vaccine)
Biothrax (anthrax vaccine adsorbed)
Boostrix (Tdap) (diphtheria toxoid / pertussis, acellular / tetanus toxoid)
Campath (alemtuzumab)
canakinumab
candida albicans extract
Candida Skin Test (candida albicans extract)
Candin (candida albicans extract)
certolizumab
Cervarix (human papillomavirus vaccine)
cholera vaccine
Cimzia (certolizumab)
cladribine
Cladribine Novaplus (cladribine)
Clopine (clozapine)
clozapine
Clozapine Synthon (clozapine)
Clozaril (clozapine)
coccidioidin skin test
Comvax (haemophilus b conjugate (prp-omp) vaccine / hepatitis b pediatric vaccine)
Cytovene (ganciclovir)
Daliresp (roflumilast)
Daptacel (DTaP) (diphtheria and tetanus toxoids / pertussis, acellular)
Decavac (Td) (diphtheria toxoid / tetanus toxoid)
deferiprone
denosumab
Denzapine (clozapine)
diphtheria and tetanus toxoids / pertussis, acellular
diphtheria toxoid / haemophilus b conjugate (hboc) vaccine / pertussis, whole cell / tetanus toxoid
diphtheria toxoid / haemophilus b conjugate (prp-t) vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid
diphtheria toxoid / haemophilus b conjugate (prp-t) vaccine / pertussis, acellular / tetanus toxoid
diphtheria toxoid / hepatitis b pediatric vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid
diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid
diphtheria toxoid / pertussis, acellular / tetanus toxoid
diphtheria toxoid / pertussis, whole cell / tetanus toxoid
diphtheria toxoid / tetanus toxoid
Diphtheria-Tetanus Toxoids, Pediatric (diphtheria toxoid / tetanus toxoid)
Dryvax (smallpox vaccine)
efalizumab
Enbrel (etanercept)
Engerix-B (hepatitis b adult vaccine)
Engerix-B Pediatric (hepatitis b pediatric vaccine)
etanercept
FazaClo (clozapine)
Ferriprox (deferiprone)
fingolimod
Fluarix (influenza virus vaccine, inactivated)
Fluarix 2012-2013 (influenza virus vaccine, inactivated)
Fluarix Quadrivalent (influenza virus vaccine, inactivated)
Flucelvax (influenza virus vaccine, inactivated)
Flucelvax 2012-2013 (influenza virus vaccine, inactivated)
FluLaval (influenza virus vaccine, inactivated)
FluLaval 2012-2013 (influenza virus vaccine, inactivated)
FluMist (influenza virus vaccine, live, trivalent)
FluMist 2012-2013 (influenza virus vaccine, live, trivalent)
Fluogen (influenza virus vaccine, inactivated)
Flushield (influenza virus vaccine, inactivated)
Fluvirin (influenza virus vaccine, inactivated)
Fluvirin 2012-2013 (influenza virus vaccine, inactivated)
Fluvirin Preservative-Free 2012-2013 (influenza virus vaccine, inactivated)
Fluzone (influenza virus vaccine, inactivated)
Fluzone 2012-2013 (influenza virus vaccine, inactivated)
Fluzone High-Dose (influenza virus vaccine, inactivated)
Fluzone High-Dose 2012-2013 (influenza virus vaccine, inactivated)
Fluzone Intradermal (influenza virus vaccine, inactivated)
Fluzone Intradermal 2012-2013 (influenza virus vaccine, inactivated)
Fluzone Preservative-Free 2012-2013 (influenza virus vaccine, inactivated)
Fluzone Preservative-Free Pediatric 2012-2013 (influenza virus vaccine, inactivated)
haemophilus b conjugate (hboc) vaccine
haemophilus b conjugate (prp-omp) vaccine
haemophilus b conjugate (prp-omp) vaccine / hepatitis b pediatric vaccine
haemophilus b conjugate (prp-t) vaccine
haemophilus b conjugate (prp-t) vaccine / meningococcal conjugate vaccine
Havrix (hepatitis a adult vaccine)
Havrix Pediatric (hepatitis a pediatric vaccine)
hepatitis a adult vaccine
hepatitis a adult vaccine / hepatitis b adult vaccine
hepatitis a pediatric vaccine
hepatitis b adult vaccine
hepatitis b pediatric vaccine
Hiberix (haemophilus b conjugate (prp-t) vaccine)
HibTITER (haemophilus b conjugate (hboc) vaccine)
Histolyn-Cyl (histoplasmin)
histoplasmin
Histoplasmin Diluted (histoplasmin)
human papillomavirus vaccine
Humira (adalimumab)
Hycamtin (topotecan)
Ilaris (canakinumab)
Imovax Rabies (rabies vaccine, human diploid cell)
Imuran (azathioprine)
Infanrix (DTaP) (diphtheria and tetanus toxoids / pertussis, acellular)
infliximab
influenza virus vaccine, h1n1, inactivated
influenza virus vaccine, h1n1, live
influenza virus vaccine, inactivated
influenza virus vaccine, live, trivalent
Ipol (poliovirus vaccine, inactivated)
Ixiaro (japanese encephalitis virus vaccine sa14-14-2)
japanese encephalitis virus vaccine nakayama
japanese encephalitis virus vaccine sa14-14-2
Je-Vax (japanese encephalitis virus vaccine nakayama)
Kineret (anakinra)
Kinrix (diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid)
leflunomide
Leustatin (cladribine)
Liquid PedvaxHIB (haemophilus b conjugate (prp-omp) vaccine)
lyme disease vaccine
LYMErix (lyme disease vaccine)
M-M-R II (measles virus vaccine / mumps virus vaccine / rubella virus vaccine)
M-R-Vax II (measles virus vaccine / rubella virus vaccine)
measles virus vaccine
measles virus vaccine / mumps virus vaccine / rubella virus vaccine
measles virus vaccine / mumps virus vaccine / rubella virus vaccine / varicella virus vaccine
measles virus vaccine / rubella virus vaccine
Menactra (meningococcal conjugate vaccine)
MenHibrix (haemophilus b conjugate (prp-t) vaccine / meningococcal conjugate vaccine)
meningococcal conjugate vaccine
meningococcal polysaccharide vaccine
Menomune (meningococcal polysaccharide vaccine)
Menomune A / C / Y / W-135 (meningococcal polysaccharide vaccine)
Menveo (meningococcal conjugate vaccine)
Meruvax II (rubella virus vaccine)
Metastron (strontium-89 chloride)
mixed respiratory vaccine
Mono-Vacc Test (OT) (tuberculin purified protein derivative)
MRV (mixed respiratory vaccine)
MSTA Mumps Skin Test Antigen (mumps skin test antigen)
Multitest CMI (skin test antigens, multiple)
mumps skin test antigen
mumps virus vaccine
mumps virus vaccine / rubella virus vaccine
Mumpsvax (mumps virus vaccine)
Pediarix (diphtheria toxoid / hepatitis b pediatric vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid)
PedvaxHIB (haemophilus b conjugate (prp-t) vaccine)
Pentacel (diphtheria toxoid / haemophilus b conjugate (prp-t) vaccine / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid)
plague vaccine
pneumococcal 13-valent vaccine
pneumococcal 23-polyvalent vaccine
pneumococcal 7-valent vaccine
Pneumovax 23 (pneumococcal 23-polyvalent vaccine)
poliovirus vaccine, inactivated
poliovirus vaccine, live, trivalent
Prevnar (pneumococcal 7-valent vaccine)
Prevnar 13 (pneumococcal 13-valent vaccine)
Prolia (denosumab)
ProQuad (measles virus vaccine / mumps virus vaccine / rubella virus vaccine / varicella virus vaccine)
Provenge (sipuleucel-T)
RabAvert (rabies vaccine, purified chick embryo cell)
rabies vaccine, human diploid cell
rabies vaccine, purified chick embryo cell
Raptiva (efalizumab)
Recombivax HB (hepatitis b pediatric vaccine)
Recombivax HB Adult (hepatitis b adult vaccine)
Recombivax HB Dialysis Formulation (hepatitis b adult vaccine)
Recombivax HB Pediatric / Adolescent (hepatitis b pediatric vaccine)
Remicade (infliximab)
rilonacept
roflumilast
Rotarix (rotavirus vaccine)
RotaShield (rotavirus vaccine)
RotaTeq (rotavirus vaccine)
rotavirus vaccine
rubella virus vaccine
samarium sm 153 lexidronam
Sclavo Test-PPD (tuberculin purified protein derivative)
Simponi (golimumab)
sipuleucel-T
skin test antigens, multiple
smallpox vaccine
sodium phosphate p32
Spherulin (coccidioidin skin test)
staphage lysate (spl)
Stelara (ustekinumab)
strontium-89 chloride
Synribo (omacetaxine)
Te Anatoxal Berna (tetanus toxoid)
teriflunomide
tetanus toxoid
Tetanus Toxoid Adsorbed (tetanus toxoid)
Tetanus Toxoid For Booster Use Only (tetanus toxoid)
Tetanus-Diphtheria Toxoids, Adult (diphtheria toxoid / tetanus toxoid)
Tetramune (diphtheria toxoid / haemophilus b conjugate (hboc) vaccine / pertussis, whole cell / tetanus toxoid)
TheraCys (bcg)
Tice BCG (bcg)
Tice BCG Vaccine (bcg)
tofacitinib
topotecan
Trichophyton Allergenic Extracts (trichophyton skin test)
trichophyton skin test
Trihibit (diphtheria toxoid / haemophilus b conjugate (prp-t) vaccine / pertussis, acellular / tetanus toxoid)
Tripedia (DTaP) (diphtheria and tetanus toxoids / pertussis, acellular)
tuberculin purified protein derivative
Tuberculin Tine Test (tuberculin purified protein derivative)
Tubersol (tuberculin purified protein derivative)
Twinrix (hepatitis a adult vaccine / hepatitis b adult vaccine)
Typhim Vi (typhoid vaccine, inactivated)
typhoid vaccine, inactivated
typhoid vaccine, live
Tysabri (natalizumab)
Valcyte (valganciclovir)
valganciclovir
Vaqta (hepatitis a adult vaccine)
Vaqta Pediatric (hepatitis a pediatric vaccine)
varicella virus vaccine
Varivax (varicella virus vaccine)
Versacloz (clozapine)
Vivotif Berna (typhoid vaccine, live)
Vivotif Berna Vaccine (typhoid vaccine, live)
Check for interactions with Zaltrap (ziv-aflibercept)
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See also...
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. Multum's drug information does not endorse drugs, diagnose patients, or recommend therapy. Multum's drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2013 Multum Information Services, Inc. The information in contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.


