zidovudine and Amphocin Interactions

Interactions between zidovudine and Amphocin (amphotericin B)

zidovudine and amphotericin B (Moderate Drug-Drug)

MONITOR: Concomitant administration of zidovudine and amphotericin B lipid complex has increased myelotoxicity and nephrotoxicity in animals. Theoretically, this interaction might occur with other amphotericin B drugs.

MANAGEMENT: If these drugs are used together, the patient's renal and hematologic function should be closely monitored.