Zestoretic Drug Interactions

Zestoretic is a multi-ingredient drug consisting of:

  • hydrochlorothiazide
  • lisinopril

Interactions with each of its ingredients have been shown below:

hydrochlorothiazide is known to interact with the following drugs:

Click on a link below to view Drug-Drug Interactions with hydrochlorothiazide.

Major Interaction Major Interactions
amiodarone, Anzemet, arsenic trioxide, cisapride, Cordarone, Cordarone I.V., dofetilide, dolasetron, droperidol, Eskalith, Eskalith-CR, Geodon, Inapsine, levomethadyl acetate, lithium, lithium carbonate, lithium carbonate extended release, lithium citrate, Lithobid, Lithonate, Lithotabs, Orap, Orlaam, Pacerone, pimozide, Propulsid, sodium biphosphate, Tikosyn, tizanidine, Trisenox, Zanaflex, ziprasidone

Moderate Interaction Moderate Interactions
5-FU, A-Hydrocort, A-Methapred, Abelcet, Abilify, Abilify Discmelt, acarbose, Accuneb, Accupril, acebutolol, Aceon, Acetocot, acetoHEXAMIDE, ACTH, ACTH Gel, ACTH-40 HP, ACTH-80, Acthar, Acthar Gel, H.P., Acthrel, Actiq, Actron, Adapin, Adbeon, Adgan, Adlone-40, Adlone-80, Adrenocot, Adrenocot L.A., Adrucil, Advil, Advil Childrens, Advil Junior Strength, Advil Liquigel, Advil Migraine, Advil Pediatric, Aflaxen, Airet, Akbeta, albuterol, albuterol extended release, alcohol, alcohol, ethyl, aldesleukin, Aleve, Aleve Caplet, Aleve Easy Open Arthritis, Aleve Gelcap, Alfenta, alfentanil, alfuzosin, alfuzosin extended release, Alka-Mints, Alkets, Alkums, All Day Allergy, Allens Junior Cough, allopurinol, Alophen, Aloprim, alprazolam, alprazolam extended release, Altace, Alupent, Amaryl, Ambien, Ambien CR, AmBisome, Ami-Natal Plus One Improved, amifostine, Amilac, Aminatal Plus, Aminatal Plus New Formula, Aminatal Plus One, Aminate, Aminate with 90 mg Iron, aminolevulinic acid topical, Amitone, amitriptyline, amoxapine, Amphocin, Amphotec, amphotericin B, amphotericin B cholesteryl sulfate, amphotericin B lipid complex, amphotericin B liposomal, Anafranil, Anaprox, Anaprox-DS, Anectine, Anectine Flo-Pack, Anemagen OB, Anergan 50, Ansaid, Antinaus 50, Apidra, Apidra OptiClik Cartridge, APO-Go, APO-Go Pen, Apokyn, apomorphine, Aquachloral Supprettes, Arduan, arformoterol, aripiprazole, Aristocort, Aristocort For Injection, Aristocort Forte, Aristopak, Aristospan Injection, Asendin, Astramorph PF, Atarax, atenolol, Ativan, atracurium, Avinza, Azmacort, baclofen, Bandi S15, benazepril, Beta-Phos/AC, Betagan, Betagan C-Cap, betamethasone, betamethasone acet-betamethasone na phosphate, betamethasone sodium phosphate, Betapace, Betapace AF, Betapace AF(obsolete), betaxolol, betaxolol ophthalmic, Betimol, Betoptic, Betoptic S, Bextra, Bisa-Plex, Bisac-Evac, bisacodyl, Bisco-Lax, Bisolax, bisoprolol, bitolterol, Black Draught, Blocadren, Boots Cough Syrup 3 Months Plus, Brethaire, Brethine, Bricanyl, Bright Beginnings, bromfenac, Bronkometer, Brovana, Bubbli-Pred, Budeprion SR, Budeprion XL, bumetanide, Bumex, Buprenex, buprenorphine, buPROPion, buPROPion 24 hour extended release, buPROPion extended release, Busodium, BuSpar, BuSpar Dividose, busPIRone, butabarbital, Butisol Sodium, Bystolic, cabergoline, Cal Oys, Cal-Gest, Cal-Nate, Calcarb, Calci Mix, Calci-Chew, calcifediol, Calciferol, Calcijex, Calcionate, Calciquid, Calcitab, calcitriol, calcium acetate, calcium carbonate, calcium chloride, calcium citrate, Calcium Concentrate, calcium glubionate, calcium gluceptate, calcium gluconate, calcium glycerophosphate, calcium lactate, Calcium Liquid Softgel, Calcium Oyster, Calcium Oyster Shell, calcium phosphate, tribasic, Calderol, Calphron, Caltrate, Caltro, Camptosar, capecitabine, Capoten, captopril, Carbacot, carbamazepine, carbamazepine extended release, Carbatrol, Cardoxin, Cardura, Cardura XL, Carduran, CareNatal DHA, carisoprodol, carteolol ophthalmic, Carters Little Pills, carvedilol, carvedilol extended release, casanthranol, cascara sagrada, Cascor, castor oil, Castor Oil, USP, Cataflam, Celebrex, celecoxib, Celestone, Celestone Phosphate, Celestone Soluspan, Celexa, Cell-U-Jec, Cenogen Ultra, Cephulac, cetirizine, Childrens Ibuprofen Berry, chloral hydrate, chlordiazepoxide, chlorproMAZINE, chlorproMAZINE extended release, chlorproPAMIDE, Chocolaxed, Cholac, cholecalciferol, cholestyramine, Cholestyramine Light, Chooz, Chromagen OB, Chronulac, cisatracurium, Cit Calcium (obsolete), citalopram, Citra pH, Citracal, Citracal Liquitab, Citracal Prenatal + DHA, Citracal Prenatal 90+DHA, Citracal Prenatal Rx, CitraNatal 90 DHA, CitraNatal DHA, CitraNatal Rx, Citrate of Magnesia, Citrate-Phos-Dex, Citroma Cherry, Citroma Lemon, Clinacort, Clinalog, Clinoril, clomiPRAMINE, clonazepam, Clopine, clorazepate, clorazepate extended release, clozapine, Clozapine Synthon, Clozaril, codeine, codeine phosphate, codeine sulfate, Colace Glycerin Suppositories, Colax, Colestid, Colestid Flavored, colestipol, Colocort, ComBi Rx, Comfort Pac with Naproxen, Compazine, Compazine Spansule, Compro, Concentrated Phillips Milk of Magnesia, Constilac, Constulose, Coreg, Coreg CR, Corgard, Corlopam, Correctol, Cort-K, Cortastat, Cortastat 10, Cortastat LA, Cortef, Cortenema, corticorelin, corticotropin, Cortifoam, cortisone, Cortone Acetate, Cortrosyn, cosyntropin, Cotolone, cyclophosphamide, cyclophosphamide lyophilized, cycloSPORINE, Cytoxan, Cytoxan Lyophilized, D 1000 IU, D3-5, D3-50, Dalalone, Dalalone D.P., Dalalone L.A., Dalmane, Darvon, Darvon-N, Daypro, Dazidox, De-Sone LA, Decadron, Decadron 5-12 Pak, Decadron Phosphate, Injectable, Decadron-LA, Decaject, Decaject L.A., Dehydrated Alcohol, Delta D3, Deltasone, Demadex, Demadex I.V., Demerol HCl, Denzapine, Dep Medalone 80, Depmedalone, Depo-Medrol, Depo-Predate (obsolete), Depoject-80, Depopred, deserpidine, Desyrel, Desyrel Dividose, Dexacen-4, Dexacort Phosphate in Respihaler, Dexacort-LA, Dexacorten, dexamethasone, dexamethasone acetate, Dexamethasone Intensol, dexamethasone sodium phosphate, Dexasone, Dexasone LA, Dexone, Dexone LA, DexPak 10 Day Taperpak, DexPak 13 DayTaperpak, Dexpak Jr. Taperpak, DHT, DHT Intensol, DiaBeta, Diabinese, Diaqua-2, Diastat, Diastat AcuDial, Diastat Pediatric, diazepam, diazoxide, Dicarbosil, diclofenac, diclofenac potassium, diclofenac sodium, diclofenac sodium extended release, diflunisal, Digitek, digitoxin, digoxin, digoxin capsule, dihydrocodeine, dihydrotachysterol, Dilaudid, Dilaudid-5, Dilaudid-HP, Diskets, disopyramide, disopyramide extended release, Dizac, Dolobid, Dolophine, Doloral, Doloral Sirop, Dopar, Dosaflex, Dostinex, doxacurium, Doxadura, doxazosin, doxazosin extended release, doxepin, doxepin topical, doxercalciferol, Doxidan Tablet, Dr Caldwell Laxative, Drisdol, Dualvit OB, Duet, Duet Chewable, Duet DHA, Duet DHA EC, Dulcogen, Dulcolax Laxative, Duphalac, DurAct, Duragesic, Duragesic-100, Duragesic-12, Duragesic-25, Duragesic-50, Duragesic-75, Duralone, Duramorph PF, Dymelor, EC-Naprosyn, Edecrin, Edecrin Sodium, Effexor, Effexor XR, Elavil, Elemental Iron-90, Emulsoil, enalapril, enalaprilat, Endep, Endocodone, Enulose, Epitol, epoprostenol, Epsom Salt, Equanil, Equetro, Equi-Natal Care, Equi-Natal M, Equi-Natal Plus, Equi-Natal Rx, Equi-Natal Z, Equilet, Equinatal 90, ergocalciferol, escitalopram, Espotabs, ETH-Oxydose, ethacrynic acid, ethanol, Ethyl Alcohol, Ethyol, etodolac, etodolac extended release, Evac-U-Gen, Evalose, Ex-Lax Chocolated, Ex-Lax Gentle Nature, Ex-Lax Maximum Relief Formula, Ex-Lax Milk of Magnesia, Ex-Lax Regular Strength Pills, Ex-lax Ultra, Extra Strength Mylanta Calci Tabs, EXUBERA, EXUBERA Combination Pack 12, EXUBERA Combination Pack 15, EXUBERA Kit, Fareston, FazaClo, Feen-A-Mint, Feldene, Fem-Natal, Femnatal, fenoldopam, fenoprofen, fentanyl, Fentora, Ferrex PC Forte, Fleet Babylax, Fleet Bisacodyl, Fleet Glycerin Suppositories Adult, Fleet Glycerin Suppositories Pediatric, Fleet Mineral Oil Enema, Fletchers Castoria, Fletchers Child Laxative Cherry, Flo-Pred, Flolan, Florinef Acetate, fludrocortisone, fluorouracil, fluoxetine, fluoxetine extended release, fluphenazine, fluphenazine decanoate, fluphenazine enanthate, fluphenazine hydrochloride, flurazepam, flurbiprofen, fluvoxamine, fluvoxamine extended release, Folbecal, Folex PFS, Foltabs, Foltabs plus DHA, Foradil Aerolizer, formoterol, Fortamet, fosinopril, Fungizone, Fungizone For Tissue Culture, furosemide, Gen Lax, Generlac, Gengraf, Genpril, Gentlax, Gentlax Tablet, Gentle Laxative, Gilseal Homecare Glycerol BP, gingko, gingko biloba, ginkgo, ginkgo biloba, glimepiride, glipiZIDE, glipiZIDE extended release, GlipiZIDE XL, Glucophage, Glucophage XR, Glucotrol, Glucotrol XL, Glumetza, glyBURIDE, glyBURIDE micronized, Glycerin, Glycerin Suppositories Maximum Strength, Glycerol, Glycerol Adult, Glycerol Infant, Glycerol Pediatric, GlycoLax, glycyrrhiza, Glynase PresTab, Glyset, guanadrel, guanethidine, guanfacine, Haldol, Haldol Decanoate, haloperidol, haloperidol decanoate, Haltran, Harmonyl, Hectorol, Heptalac, Hexadrol, Hexadrol Phosphate, Hi-Nate 90, Hiprex, Humalog, Humalog Cartridge, Humalog KwikPen, Humalog Pen, Humulin L, Humulin N, Humulin N Pen, Humulin R, Humulin R (Concentrated), Humulin U, Hydeltra-T.B.A., Hydeltrasol, hydrocortisone, hydrocortisone acetate, hydrocortisone cypionate, hydrocortisone hemisuccinate, hydrocortisone sodium phosphate, Hydrocortisone Sodium Succinate, Hydrocortone, Hydrocortone Phosphate, Hydromorph Contin, hydromorphone, hydromorphone extended release, Hydrostat IR, hydrOXYzine, hydrOXYzine hydrochloride, hydrOXYzine pamoate, Hylorel, Hyperstat, Hytakerol, Hytrin, Hyzine, Ibu, IBU-200, Ibu-4, Ibu-6, Ibu-8, Ibu-Tab, ibuprofen, Ibuprofen PMR, Icar Prenatal, Icar Prenatal Chewable Calcium, Icare Prenatal Rx, Ichthammol Glycerin, Iletin II Lente Pork, Iletin II NPH Pork, Iletin II Regular Pork, Iletin Lente, Iletin NPH, Iletin Regular, iloprost, imipramine, imipramine pamoate, Inatal Advance, Inatal Ultra, Inderal, Inderal LA, Indocin, Indocin SR, indomethacin, indomethacin extended release, Infumorph, Innerclean, InnoPran XL, insulin, insulin analog, insulin aspart, insulin aspart protamine, insulin detemir, insulin glargine, insulin glulisine, insulin inhalation, rapid acting, insulin isophane, Insulin Lente Pork, insulin lispro, insulin lispro protamine, Insulin Purified NPH Pork, Insulin Purified Regular Pork, insulin regular, insulin zinc, insulin zinc extended, insulin, lente, insulin, NPH, insulin, ultralente, Invega, Ionsys, irinotecan, Ismelin, isoetharine, Istalol, Januvia, Kadian, Ken-Jec 40, Kenaject-40, Kenalog-10, Kenalog-40, Kerlone, ketoprofen, ketoprofen extended release, ketorolac, Key-Pred, Key-Pred SP, Klonopin, Klonopin Wafer, Kondremul Plain, Kristalose, labetalol, Lactocal-F, lactulose, Lanoxicaps, Lanoxin, Lantus, Lantus OptiClik Cartridge, Lantus Solostar Pen, Larodopa, Lasix, Laxative Gentle Suppositories, Leader Mineral Oil Enema, Leader Naproxen Sodium, Lente insulin, levalbuterol, Levemir, Levemir FlexPen, Levemir InnoLet, Levemir PenFill, Levobunolol, levobunolol ophthalmic, levocetirizine, levodopa, LEVRIX, Levulan Kerastick, Lexapro, Librium, licorice, Lioresal, Lioresal Intrathecal, Liqui Doss, Liquid Pred, lisinopril, Lo-Aqua, Lodine, Lodine XL, Lopressor, Lopurin, lorazepam, Lotensin, loxapine, Loxitane, Loxitane C, Loxitane IM, Ludiomil, Luminal, Luvox, Luvox CR, M-Eslon, M-Oxy, M-PREDNISolone, M. O. S., Maalox Antacid Barrier, Maalox Childrens', Maalox Quick Dissolve, Maalox Quick Dissolve Extra Strength, Maalox Quick Dissolve Maximum Strength, Maalox Regular Strength, Magic Bullet, magnesium citrate, magnesium hydroxide, magnesium sulfate, Mandelamine, maprotiline, maraviroc, Marnatal-F Plus, Materna, Maternal 90, Maternity, Maternity plus Beta Carotene, Maternity Vitamin Low Iron, Maternity-90, Mavik, Maxair, Maxair Autohaler, Maxinate, MB-TAB, meclofenamate, Meclomen, Med-Jec-40, Medicort, Medidex, Medidex LA, Medilax, Medipred, Medralone, Medralone 40, Medralone 80, Medrol, Medrol Dosepak, mefenamic acid, Mellaril, Mellaril-S, meloxicam, Menadol, meperidine, meprobamate, mesoridazine, Metaprel, metaproterenol, metformin, metformin extended release, Methacort 40, Methacort 80, methadone, Methadose, methdilazine, methenamine, methenamine hippurate, methenamine mandelate, methocarbamol, methotrexate, Methotrexate Sodium, Preservative Free, methyl aminolevulinate topical, Methylcotol, Methylcotolone, Methylpred DP, methylPREDNISolone, methylPREDNISolone acetate, MethylPREDNISolone Dose Pack, methylPREDNISolone sodium succinate, Meticorten, metipranolol ophthalmic, metocurine, metoprolol, metoprolol extended release, metoprolol succinate, Metoprolol Succinate ER, metoprolol tartrate, Metubine Iodide, Metvixia, Mg hydroxide, Mg sulfate, Micronase, midazolam, Midol Extended Relief, Midol IB, Midol Maximum Strength Cramp Formula, miglitol, Milk of Magnesia, Milkinol, Millipred, Miltown, mineral oil, Mineral Oil, Heavy, Mineral Oil, Light, Minipress, MiraLax, mirtazapine, Mission Prenatal, Mission Prenatal FA, Mission Prenatal HP, Mission Prenatal Rx, Mitran, Mivacron, mivacurium, Mobic, Modane, moexipril, Monopril, morphine, morphine 24 hour extended release, morphine extended release, Morphine IR, Morphine LP Epidural, morphine preservative-free, Morphine Rapi-Ject, Morphitec, Motrin, Motrin Childrens, Motrin IB, Motrin Infant Drops, Motrin Junior Strength, Motrin Migraine Pain, Motrin Pediatric, MS, MS Contin, MS/S, MSIR, Multifol Plus, multivitamin, prenatal, Muri-Lube, Mylanta Child, Mynatal, Mynatal FC, Mynatal Plus, Mynatal PN, Mynatal PN Forte, Mynatal Rx, Mynatal Ultracap, Mynatal Z, Mynate 90 Plus, nabumetone, nadolol, nalbuphine, Nalfon, Naprelan '375', Naprelan '500', Naprosyn, naproxen, naproxen sodium, Naproxen Sodium DS, naproxen sodium extended release, Natacaps, Natachew, Natafolic-OB, Natafolic-PN, Natafort, NatalCare, NatalCare Advanced, NatalCare Advanced-RF, NatalCare CFE 60, Natalcare Pic, Natalcare Pic Forte, Natalcare Plus, Natalcare Rx, NatalCare Three, Natalcare(obsolete), Natalfirst, Natalins, Natalins Rx, Natarex, Natatab CFe, Natatab FA, Natatab Rx, nateglinide, Natelle, Natelle C, Natelle Plus with DHA, Natelle Prefer, Natelle-ez, Natures Remedy, nebivolol, Neevo, nefazodone, Neo-Calglucon, Neo-Forte, Neoloid, NeoProfen, Neoral, Neosar, Nephro Calci, Nestabs, Nestabs CBF, Nestabs FA, Nestabs Rx, New Advanced Formula Prenatal Z, Niferex PN Forte, Niferex-PN, Nimbex, Niravam, Norcuron, Norlac RX, Normodyne, Norpace, Norpace CR, Novanatal, NovaStart, Novastart (obsolete), Novolin L, Novolin N, Novolin N Innolet, Novolin N PenFill, Novolin R, Novolin R Innolet, Novolin R PenFill, NovoLog, NovoLog FlexPen, NovoLog PenFill, NPH insulin, Nubain, Nuprin, Nuromax, NutriNate, Nutrispire, O-Cal Prenatal, O-Cal-FA, OB Complete, OB Complete with DHA, Ob-20, Obegyn, Obnate 90, Obtrex, Ocupress, olanzapine, olopatadine nasal, OMS, opium, Opium Deodorized, OptiNate, OptiPranolol, Oramorph SR, Orapred, Orapred ODT, Orasone, Orinase, Ormazine, Orudis, Orudis KT, Oruvail, Os-Cal, Os-Cal 500, Osmoglyn, oxaprozin, oxazepam, oxycodone, oxycodone extended release, OxyContin, Oxyfast, OxyIR, Oysco 500, Oyst Cal, Oyst Cal 500, Oyster, Oyster Cal, Oyster Cal 500, Oyster Calcium, Oyster Shell, oyster shell calcium, Oyster Shell Calcium 500, paliperidone, Palladone, Palladone SR, Pan OB Forte, pancuronium, Par-F, Paral, paraldehyde, Paregoric, paricalcitol, paroxetine, paroxetine extended release, paroxetine mesylate, Patanase, Pavulon, Paxil, Paxil CR, Pedia-Lax, Pedia-Lax Liquid, Pediacare Fever, Pediapred, Pentazine, pentazocine, Pepto Children's, Percolone, Perdiem Overnight, Perforomist, perindopril, Permitil, perphenazine, Pexeva, Phenadoz, Phenazine 50, Phenergan, Phenergan Fortis, phenobarbital, Phenoject-50, Phenolax, phenolphthalein, phenylbutazone, Phillips Milk of Magnesia, PhosLo, PhosLo Gelcap, pindolol, pipecuronium, pirbuterol, piroxicam, polyethylene glycol 3350, Ponstel, Posture, PP-Cap, Pramilet FA, Prandin, prazosin, Pre-H-Cal, Precare, Precare Conceive, Precare Premier, Precose, Pred-Ject-50, Predacort 50, Predacorten, Predaject-50, Predalone 50, Predate-50, Predcor, Predicort RP, Predicort-50, Prednicen-M, Prednicot, prednisoLONE, prednisoLONE acetate, prednisoLONE sodium phosphate, prednisoLONE tebutate, predniSONE, PreferaOB, Prelief, Prelone, Premesis Rx, PrenaFirst, Prenatabs CBF, Prenatabs FA, Prenatabs OBN, Prenatabs Rx, Prenatal 1 Plus 1, Prenatal 1 Plus 1 (Low Iron), Prenatal 19, Prenatal AD, Prenatal Elite, Prenatal H, Prenatal Low Iron, Prenatal MR 90, Prenatal MR 90 Fe, Prenatal MTR with Selenium, prenatal multivitamin, Prenatal Multivitamins, Prenatal Plus, Prenatal Plus Iron, Prenatal Plus with 27 mg Iron, Prenatal Plus with Beta-Carotene, Prenatal Rx, Prenatal Rx 1, Prenatal S, Prenatal Z Advanced Formula, Prenatal-U, Prenate 90, Prenate Advance, Prenate Advanced Formula, Prenate DHA, Prenate Elite, Prenate GT, Prenate Ultra, Prenavite, Prenavite FC, Prenavite PC, Prenazyme 1+1, Preterna, Prevalite, Prevalite Packets, Pri-Cortin 50, PrimaCare, PrimaCare Advantage, PrimaCare One, Primethasone, Prinivil, Pro-Med, ProAir HFA, prochlorperazine, prochlorperazine extended release, Procot, Proglycem, Proleukin, Prolixin, Prolixin Decanoate, Prolixin Enanthate, Promacot, promazine, promethazine, Promethegan, propoxyphene, propoxyphene hydrochloride, propoxyphene napsylate, propranolol, propranolol extended release, Prorex, prostacyclin, protamine zinc insulin, Proventil, Proventil HFA, Proventil Repetabs, Prozac, Prozac Weekly, Prudoxin, Pruet DHA, Prulet, Purge, Q-Profen, Quelicin Chloride, Questran, Questran Light, Questran Light Packets, Questran Packets, quetiapine, quetiapine extended release, quinapril, ramipril, rapacuronium, Rapiflux, Raplon, Rauwolfemms, Rauwolfia 1X, rauwolfia serpentina, Ravin, regular insulin, Relafen, Relion Novolin N, ReliOn/Novolin R, Remeron, Remeron SolTab, Remodulin, repaglinide, Rescudose, reserpine, Respirol, Restoril, Rezine,