zelnorm and Estinyl Interactions

Interactions between zelnorm(tegaserod) and Estinyl (ethinyl estradiol)

ethinyl estradiol and tegaserod (Minor Drug-Drug)

Tegaserod decreased levonorgestrel plasma concentrations by less than 10% in a clinical study with a low-dose triphasic oral contraceptive (n=45). The mechanism is unknown. There were no changes in ethinyl estradiol concentrations or in contraceptive efficacy. No action is necessary.