zantac-75 and Aleve caplet Interactions

Interactions between zantac-75(ranitidine) and Aleve caplet (naproxen)

naproxen and ranitidine (Moderate Drug-Drug)

GENERALLY AVOID: The concomitant administration of H2 blockers may increase the dissolution rate of enteric-coated naproxen, causing the drug to be released in the stomach instead of the small intestine.

MANAGEMENT: H2 antagonists should be avoided in patients taking enteric-coated formulations of naproxen.