yohimbine and Astramorph pf Interactions

Interactions between yohimbine and Astramorph pf (morphine)

morphine and yohimbine (Minor Drug-Drug)

A double-blind, placebo-controlled study of patients with postoperative dental pain found that while yohimbine itself did not affect pain, the overall analgesic effect of morphine was significantly enhanced in the presence of yohimbine. The mechanism of interaction is unknown. Additional research involving other pain states is needed.