xopenex and Adapin Interactions

Interactions between xopenex(levalbuterol) and Adapin (doxepin)

doxepin and levalbuterol (Moderate Drug-Drug)

MONITOR: Tricyclic antidepressants (TCAs) can potentiate the cardiovascular effects of beta adrenergic agonists. TCAs possess peripheral sympathetic activity and can increase blood pressure and heart rate, thus they may have additive effects with beta adrenergic agonists.

MANAGEMENT: Caution is advised if beta adrenergic agonists are used with TCAs, or within two weeks of discontinuation of the latter. Pulse and blood pressure should be closely monitored.