Drug interactions between VePesid and Vincasar PFS
Results for the following 2 drugs: |
|
|---|---|
| VePesid (etoposide) | |
| Vincasar PFS (vincristine) | |
Interactions between your selected drugs
etoposide ⇔ vincristine
Applies to: VePesid (etoposide) and Vincasar PFS (vincristine)
Concurrent administration of vincristine and etoposide may lead to an earlier onset and/or an increased severity of side effects. The mechanism of action is inhibition of the metabolism of both drugs by a hepatic cytochrome P-450 isoenzyme in the CYP 3A subfamily. The clinical significance of this interaction has not been established. If vincristine and etoposide are used concomitantly, caution and close observation are advised.
See also...
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