Interactions between venofer(iron sucrose) and Aquasol e (vitamin E)
vitamin E and iron sucrose (Moderate Drug-Drug)
MONITOR: Limited data suggest that vitamin E may diminish the therapeutic response to iron therapy in patients with iron deficiency anemia. The mechanism has not been established. In a group of 26 anemic children treated with iron dextran for 3 days, nine patients who also received vitamin E (200 units starting one day before iron dextran) had a reticulocyte response of only 4.4%, compared to 14.4% in the other patients. The patients who received vitamin E also had reduced hemoglobin levels and lower hematocrit.
MANAGEMENT: Patients receiving iron therapy for iron deficiency anemia should be monitored for potentially reduced hematologic response if vitamin E is administered concomitantly.
