vancomycin and Doxacurium Interactions

Interactions between vancomycin and Doxacurium (doxacurium)

vancomycin and doxacurium (Moderate Drug-Drug)

MONITOR: Like other polypeptide antibiotics, vancomycin may prolong apnea and respiratory paralysis after use of neuromuscular blocking agents. The mechanism may be related to decreased intracellular potassium or decreased ionized serum calcium.

MANAGEMENT: Patients should be monitored for excessive and prolonged neuromuscular blockade.