urso and Neoral Interactions

Interactions between urso(ursodiol) and Neoral (cycloSPORINE)

cycloSPORINE and ursodiol (Minor Drug-Drug)

Bile acid salts may increase the bioavailability of oral cyclosporine. Data have been conflicting. The mechanism and clinical significance are unknown. No action is necessary; however, clinicians should be aware of the possibility of an interaction.