uni-dur and Halothane Interactions

Interactions between uni-dur(theophylline) and Halothane (halothane)

theophylline and halothane (Major Drug-Drug)

GENERALLY AVOID: The administration of halothane following theophylline administration has been reported to result in ventricular tachycardia and, in one case, ventricular fibrillation. Halothane increases the arrhythmogenic potential of catecholamines. Theophylline appears to enhance the release of catecholamines.

MANAGEMENT: This combination should be avoided if possible. Halothane may interact in a similar manner with other methylxanthines.