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Drug Interactions between Trizivir and Valcyte

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

zidovudine valGANciclovir

Applies to: Trizivir (abacavir / lamivudine / zidovudine) and Valcyte (valganciclovir)

Using zidovudine together with valGANciclovir may increase the risk of side effects affecting the blood leading to decreased levels of blood cells (white blood cells, red blood cells, and platelets). Talk to your doctor if you have any questions or concerns. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Your doctor may already be aware of the interaction, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

valGANciclovir food

Applies to: Valcyte (valganciclovir)

Food can enhance the levels of valGANciclovir in your body. To ensure maximal oral absorption, valGANciclovir should be administered with or immediately after a meal. This will make it easier for your body to absorb the medication.

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Minor

zidovudine food

Applies to: Trizivir (abacavir / lamivudine / zidovudine)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.