trental and Toradol Interactions

Interactions between trental(pentoxifylline) and Toradol (ketorolac)

ketorolac and pentoxifylline (Moderate Drug-Drug)

GENERALLY AVOID: The concomitant use of pentoxifylline and ketorolac may increase the risk of bleeding. Bleeding events have been reported in postoperative patients who were receiving both drugs, although causality was not established. Pentoxifylline and ketorolac individually have been associated with prothrombin time prolongations and bleeding.

MANAGEMENT: Concurrent use should generally be avoided.