Topotecan Drug Interactions

topotecan is known to interact with the following drugs:

Click on a link below to view Drug-Drug Interactions with topotecan.

Major Interaction Major Interactions
adalimumab, Arava, Attenuvax, BCG, carboplatin, Carboplatin Novaplus, certolizumab, Cimzia, cisplatin, Clopine, clozapine, Clozapine Synthon, Clozaril, Denzapine, Dryvax, Eloxatin, Enbrel, Enbrel Prefilled Syringe, Enbrel SureClick, etanercept, FazaClo, FluMist, Humira, Humira Pen, Humira Pen Crohn's Disease Starter Package, infliximab, influenza virus vaccine, live, trivalent, leflunomide, measles virus vaccine, Meruvax II, mumps virus vaccine, Mumpsvax, natalizumab, OPV, Orimune, oxaliplatin, Paraplatin, Platinol (Restricted Access), Platinol-AQ, poliovirus vaccine, live, trivalent, Quadramet, Remicade, Rotarix, RotaShield, RotaTeq, rotavirus vaccine, rubella virus vaccine, Sabin, samarium sm 153 lexidronam, smallpox vaccine, thalidomide, Thalomid, TheraCys, Tice BCG Vaccine, TOPV, typhoid vaccine, live, Tysabri, varicella virus vaccine, Varivax, Vivotif Berna, yellow fever vaccine, YF-Vax, Zaponex, Zostavax, zoster vaccine live

Moderate Interaction Moderate Interactions
5-FU, Abraxane, ActHIB, Acthib (obsolete), actinomycin D, Adriamycin, Adriamycin RDF, Adrucil, Afluria, alatrofloxacin, aldesleukin, alefacept, alemtuzumab, Alkeran, Alkeran I.V., altretamine, Amevive, anakinra, anthrax vaccine adsorbed, Aplisol, Aplitest, ara-C, Arcalyst, Arranon, asparaginase, Avelox, Avelox I.V., Azasan, azathioprine, bexarotene, BiCNU, Biothrax, Blenoxane, bleomycin, busulfan, Busulfex, Campath, Camptosar, candida albicans extract, Candida Skin Test, Candin, capecitabine, carmustine, Ceenu, Cerubidine, chlorambucil, cholera vaccine, Cinobac, cinoxacin, Cipro, Cipro Cystitis Pack, Cipro I.V., Cipro XR, ciprofloxacin, ciprofloxacin extended release, cladribine, Cladribine Novaplus, clofarabine, Clolar, coccidioidin skin test, Cosmegen, cyclophosphamide, cyclophosphamide lyophilized, cytarabine, cytarabine arabinoside, Cytosar, Cytosar-U, Cytovene, Cytoxan, Cytoxan Lyophilized, dacarbazine, dactinomycin, DAUNOrubicin, DAUNOrubicin liposomal, Daunoxome, denileukin diftitox, docetaxel, Doxil, DOXOrubicin, DOXOrubicin liposomal, Droxia, DTIC-Dome, efalizumab, Ellence, Elspar, Engerix-B, Engerix-B Pediatric, enoxacin, epirubicin, Ergamisol, Etopophos, etoposide, etoposide phosphate, Factive, filgrastim, Floxin, Floxin I.V., floxuridine, Fluarix, Fludara, fludarabine, FluLaval, Fluogen, fluorouracil, Flushield, FluShield (obsolete), Fluvirin, Fluvirin Preservative-Free, Fluzone, Fluzone PFS, Fluzone Preservative-Free, Fluzone Preservative-Free Pediatric, Fluzone SV, Fluzone WV, Folex PFS, FUDR, G-CSF, ganciclovir, Gardasil, gatifloxacin, gemcitabine, gemifloxacin, gemtuzumab, Gemzar, Gleevec, Gliadel, GM-CSF, grepafloxacin, haemophilus b conjugate (HbOC) vaccine, haemophilus b conjugate (PRP-OMP) vaccine, haemophilus b conjugate (PRP-T) vaccine, haemophilus b conjugate vaccine (obsolete), haemophilus b diphtheria conjugate vaccine, haemophilus b Neisseria conjugate vaccine, haemophilus b tetanus conjugate vaccine, Havrix, Havrix (obsolete), Havrix Pediatric, Havrix Pediatric (obsolete), hepatitis A adult vaccine, hepatitis A pediatric vaccine, hepatitis A vaccine (obsolete), hepatitis B vaccine, Herceptin, Hexalen, HibTITER, Hibtiter (obsolete), Histolyn-Cyl, histoplasmin, Histoplasmin Diluted, HPV, human papillomavirus vaccine, Hydrea, hydroxyurea, Idamycin PFS, idarubicin, Ifex, ifosfamide, imatinib, Imovax Rabies, Imovax Rabies (obsolete), Imovax Rabies I.D. (obsolete), Imuran, influenza virus vaccine, inactivated, interferon alfa-2a, interferon alfa-2b, Intron A, Ipol, IPV, irinotecan, Japanese encephalitis virus vaccine, Je-Vax, Kepivance, Kineret, Leukeran, Leukine, Leustatin, levamisole, Levaquin, Levaquin Leva-Pak, levofloxacin, Liquid PedvaxHIB, lomefloxacin, lomustine, Lyme disease vaccine, LYMErix, Matulane, Maxaquin, mechlorethamine, melphalan, Menactra, meningococcal conjugate vaccine, meningococcal polysaccharide vaccine, Menomune A/C/Y/W-135, mercaptopurine, Metastron, methotrexate, Methotrexate Sodium, Preservative Free, Mithracin, mitomycin, mitoxantrone, mixed respiratory vaccine, Mono-Vacc Test (O.T.), moxifloxacin, MSTA Mumps Skin Test Antigen, Multitest CMI, mumps skin test antigen, Mustargen, Mutamycin, Myleran, Mylocel, Mylotarg, nalidixic acid, Navelbine, Neggram, nelarabine, Neosar, Neulasta, Neupogen, Nipent, norfloxacin, Noroxin, Novantrone, ofloxacin, Omnihib, Oncovin, Ontak, Onxol, paclitaxel, paclitaxel protein-bound, palifermin, Pedvax HIB, Pegasys, pegfilgrastim, peginterferon alfa-2a, peginterferon alfa-2b, PegIntron, PegIntron Redipen, Penetrex, pentostatin, Pharmorubicin PFS, Pharmorubicin RDF, plague vaccine, plicamycin, pneumococcal 23-valent vaccine, pneumococcal 23-valent vaccine (obsolete), pneumococcal 7-valent vaccine, Pneumovax 23, Pneumovax 23 (obsolete), Pnu-Imune 23 (obsolete), poliovirus vaccine, inactivated, Prevnar, primaquine, primaquine phosphate, procarbazine, Prohibit, Proleukin, Proquin XR, Purinethol, RabAvert, RabAvert (obsolete), Rabies Vaccine (obsolete), rabies vaccine, human diploid cell, rabies vaccine, purified chick embryo cell, Raptiva, Raxar, Recombivax HB, Recombivax HB Adult, Recombivax HB Dialysis Formulation, Recombivax HB Pediatric/Adolescent, Rheumatrex Dose Pack, rilonacept, Rituxan, rituximab, Roferon-A, sargramostim, Sclavo Test-PPD, skin test antigens, multiple, sodium phosphate p32, sparfloxacin, Spherulin, SPL, Staphage Lysate (SPL), streptozocin, strontium-89 chloride, Tarabine PFS, Targretin, Taxol, Taxotere, Temodar, temozolomide, teniposide, Tequin, Tequin Teqpaq, Tetanus Toxoid, Tetanus Toxoid Adsorbed, Tetanus Toxoid For Booster Use Only, thioguanine, Thioplex, thiotepa, Toposar, trastuzumab, Trexall, Trichophyton Allergenic Extracts, trichophyton skin test, trovafloxacin, Trovan, tuberculin purified protein derivative, Tuberculin Tine Test, Tubersol, Typhim VI, typhoid vaccine, inactivated, uracil mustard, Valcyte, valganciclovir, Vaqta, Vaqta (obsolete), Vaqta Pediatric, Vaqta Pediatric (obsolete), Velban, VePesid, vinBLAStine, Vincasar PFS, vinCRIStine, vinorelbine, Vumon, Xeloda, Zagam, Zagam Respipac, Zanosar

Minor Interaction Minor Interactions
Alert, Cafcit, Caffedrine, caffeine, caffeine extended release, Keep Alert, Lucidex, No Doz, NoDoz Maximum Strength, Pep-Back Peak Performance, Stat Awake, Stay Alert, Stay Awake, Verv, Vivarin, Wakespan

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