ticlid and Activase Interactions

Interactions between ticlid(ticlopidine) and Activase (alteplase)

ticlopidine and alteplase (Moderate Drug-Drug)

MONITOR: Drugs that inhibit platelet function may increase the risk of bleeding when administered prior to, during, or after thrombolytic therapy.

MANAGEMENT: Careful monitoring for signs of bleeding, particularly at arterial puncture wounds, is recommended when thrombolytics are used concurrently or sequentially with antiplatelet agents.